Protein Alignment Hsp22 and Hspb2

DIOPT Version :10

• Sequence 1: NP_001027114.1
• Gene: Hsp22 / 3772576
• FlyBaseID: FBgn0001223
• Length: 174
• Species: Drosophila melanogaster
• Sequence 2: NP_077761.3
• Gene: Hspb2 / 69253
• MGIID: 1916503
• Length: 182
• Species: Mus musculus
• Alignment Length: 147
• Identity: 36/147 - (24%)
• Similarity: 62/147 - (42%)
• Gaps: 19/147 - (12%)

  Fly    24 FHAFFHEPPVWSVALPRNWQQIARWQE--QEFAPPATVNKDGYKLTLDVKDYS--ELKVKVLDES 84
            :|.::..|            :.||..|  :..|....:::..::..|||..::  |:.|:.:|.
Mouse    44 YHGYYVRP------------RAARAGEGARAGASELRLSEGKFQAFLDVSHFTPDEVTVRTVDN- 95

  Fly    85 VVLVEGKSEQQEAEQGGYSSRHFLRRFVLPEGYEADKVTSTLSSDGVLTISVPNPPGVQETLKER 149
             :|.......|..::.|:.||.|.|.:|||...:..:|.:.||.||:|.:..|. .|.....:..
Mouse    96 -LLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPR-GGRHLDTEVN 158

  Fly   150 EVTIEQTGEPAKKSAEE 166
            ||.|.....|.....||
Mouse   159 EVYISLLPAPPDPEEEE 175

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp22	NP_001027114.1	metazoan_ACD	61..138	CDD:107247	22/78 (28%)
Hspb2	NP_077761.3	Crystallin	<21..51	CDD:425732	1/6 (17%)
		alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.	67..148	CDD:469641	22/82 (27%)