DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsp22 and hspb2

DIOPT Version :9

Sequence 1:	NP_001027114.1	Gene:	Hsp22 / 3772576	FlyBaseID:	FBgn0001223	Length:	174	Species:	Drosophila melanogaster
Sequence 2:	NP_001017744.1	Gene:	hspb2 / 550439	ZFINID:	ZDB-GENE-050417-260	Length:	169	Species:	Danio rerio

Alignment Length:	181	Identity:	45/181 - (24%)
Similarity:	81/181 - (44%)	Gaps:	36/181 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 RSLPMFWRMA--EEMARMPRL--------SSP--------FHAFFHEPPVWSVALPRNWQQIARW 48
            |::|..:.|:  .||...||:        .||        :|.::..|.: :..|.|.:.|:
Zfish     4 RTVPHAYPMSMDYEMCTPPRIYDQNFAEALSPKELLAPVLYHGYYIRPRI-NKQLERGFSQV--- 64

  Fly    49 QEQEFAPPATVNKDGYKLTLDVKDYS--ELKVKVLDESVVLVEGKSEQQEAEQGGYSSRHFLRRF 111
             |.|        .|.|::.|||..::  |:.|:.:|.  :|.......|..:|.|:.||.|.|.:
Zfish    65 -ESE--------DDWYRVLLDVCQFTPDEISVRTVDN--LLEVSARHAQRMDQHGFVSREFTRTY 118

  Fly   112 VLPEGYEADKVTSTLSSDGVLTISVP-NPPGVQETLKEREVTIEQTGEPAK 161
            :||.|.:...|..:||.||:|.|..| ....::..:.:.::.:|:....:|
Zfish   119 ILPMGVDPLLVQVSLSHDGILCIQAPRKTEDLEPQINQLKIKVEKKESTSK 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsp22	NP_001027114.1	IbpA	17..154	CDD:223149	38/155 (25%)
Hsp22	NP_001027114.1	metazoan_ACD	61..138	CDD:107247	27/79 (34%)
hspb2	NP_001017744.1	ACD_HspB2_like	63..145	CDD:107231	29/95 (31%)
hspb2	NP_001017744.1	IbpA	<64..162	CDD:223149	29/111 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582845
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840