Protein Alignment Hsp22 and Hspb1

DIOPT Version :10

• Sequence 1: NP_001027114.1
• Gene: Hsp22 / 3772576
• FlyBaseID: FBgn0001223
• Length: 174
• Species: Drosophila melanogaster
• Sequence 2: NP_114176.4
• Gene: Hspb1 / 24471
• RGDID: 61306
• Length: 206
• Species: Rattus norvegicus
• Alignment Length: 187
• Identity: 53/187 - (28%)
• Similarity: 79/187 - (42%)
• Gaps: 53/187 - (28%)

  Fly     5 PMFWRMAEEMARMPRLSSPFHAFFHEPPVWSVALPRNWQQIARW---------------QEQEFA 54
            |...|:.::...:||.          |..||     .|...|.|               .....|
  Rat    24 PAHSRLFDQAFGVPRF----------PDEWS-----QWFSSAGWPGYVRPLPAATAEGPAAVTLA 73

  Fly    55 PPA---TVNK-------------DGYKLTLDVKDYS--ELKVKVLDESVVLVEGKSEQQEAEQGG 101
            .||   .:|:             |.::::|||..::  ||.||. .|.||.:.||.|:::.|. |
  Rat    74 APAFSRALNRQLSSGVSEIRQTADRWRVSLDVNHFAPEELTVKT-KEGVVEITGKHEERQDEH-G 136

  Fly   102 YSSRHFLRRFVLPEGYEADKVTSTLSSDGVLTISVPNPPGVQETLKEREVTIEQTGE 158
            |.||.|.|::.||.|.:...|:|:||.:|.||:..|.|..|.::   .|:||..|.|
  Rat   137 YISRCFTRKYTLPPGVDPTLVSSSLSPEGTLTVEAPLPKAVTQS---AEITIPVTFE 190

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp22	NP_001027114.1	metazoan_ACD	61..138	CDD:107247	31/91 (34%)
Hspb1	NP_114176.4	Interaction with TGFB1I1. /evidence=ECO:0000269|PubMed:11546764	74..206		42/122 (34%)
		ACD_HspB1_like	88..173	CDD:107230	31/86 (36%)