Protein Alignment Hsp22 and Hspb6

DIOPT Version :10

• Sequence 1: NP_001027114.1
• Gene: Hsp22 / 3772576
• FlyBaseID: FBgn0001223
• Length: 174
• Species: Drosophila melanogaster
• Sequence 2: NP_001012401.1
• Gene: Hspb6 / 243912
• MGIID: 2685325
• Length: 162
• Species: Mus musculus
• Alignment Length: 146
• Identity: 48/146 - (32%)
• Similarity: 70/146 - (47%)
• Gaps: 36/146 - (24%)

  Fly    11 AEEMARMPRLSSPFHAFFHEPPVWSVALPRNWQQIARWQEQEFAPPATVNKD-GY-KLTLDVKDY 73
            ||..:..|...:|:  :...|   ||||                |.|.|:.| || .:.||||.:
Mouse    40 AELASLCPAAIAPY--YLRAP---SVAL----------------PTAQVSTDSGYFSVLLDVKHF 83

  Fly    74 --SELKVKVLDESVVLVEGKSEQQEAEQGGYSSRHFLRRFVLPEGYEADKVTSTLSSDGVLTI-- 134
              .|:.|||:|:.|. |..:.|::..|. |:.:|.|.||:.||.|.:...|||.||.:|||:|
Mouse    84 LPEEISVKVVDDHVE-VHARHEERPDEH-GFIAREFHRRYRLPPGVDPAAVTSALSPEGVLSIQA 146

  Fly   135 -------SVPNPPGVQ 143
                   .:|:||..:
Mouse   147 TPASAQAQLPSPPAAK 162

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp22	NP_001027114.1	metazoan_ACD	61..138	CDD:107247	33/89 (37%)
Hspb6	NP_001012401.1	Involved in stabilization of the HSPB1:HSBP6 heterodimer. /evidence=ECO:0000250|UniProtKB:O14558	1..72		13/52 (25%)
		Crystallin	3..62	CDD:425732	7/26 (27%)
		ACD_HspB4-5-6	66..148	CDD:107233	34/83 (41%)