Protein Alignment Hsp22 and CRYAB

DIOPT Version :10

• Sequence 1: NP_001027114.1
• Gene: Hsp22 / 3772576
• FlyBaseID: FBgn0001223
• Length: 174
• Species: Drosophila melanogaster
• Sequence 2: NP_001876.1
• Gene: CRYAB / 1410
• HGNCID: 2389
• Length: 175
• Species: Homo sapiens
• Alignment Length: 163
• Identity: 55/163 - (33%)
• Similarity: 85/163 - (52%)
• Gaps: 27/163 - (16%)

  Fly    23 PFHA-------FFHE--------PPVWSVA----LPRNWQQIARWQEQEFAPPATVNKDGYKLTL 68
            |||:       ||.|        |...|::    .|.::.:...|.:...: ...:.||.:.:.|
Human    16 PFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSWFDTGLS-EMRLEKDRFSVNL 79

  Fly    69 DVKDYS--ELKVKVLDESVVLVEGKSEQQEAEQGGYSSRHFLRRFVLPEGYEADKVTSTLSSDGV 131
            |||.:|  |||||||.: |:.|.||.|:::.|. |:.||.|.|::.:|...:...:||:||||||
Human    80 DVKHFSPEELKVKVLGD-VIEVHGKHEERQDEH-GFISREFHRKYRIPADVDPLTITSSLSSDGV 142

  Fly   132 LTISVPNPPGVQETLKEREVTIEQTGEPAKKSA 164
            ||:   |.|..|.:..||.:.|.:..:||..:|
Human   143 LTV---NGPRKQVSGPERTIPITREEKPAVTAA 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp22	NP_001027114.1	metazoan_ACD	61..138	CDD:107247	36/78 (46%)
CRYAB	NP_001876.1	Crystallin	1..55	CDD:425732	9/38 (24%)
		ACD_alphaB-crystallin_HspB5	67..150	CDD:107246	38/87 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	146..175		9/27 (33%)