Protein Alignment Hsp22 and CRYAA

DIOPT Version :10

• Sequence 1: NP_001027114.1
• Gene: Hsp22 / 3772576
• FlyBaseID: FBgn0001223
• Length: 174
• Species: Drosophila melanogaster
• Sequence 2: NP_000385.1
• Gene: CRYAA / 1409
• HGNCID: 2388
• Length: 173
• Species: Homo sapiens
• Alignment Length: 147
• Identity: 44/147 - (29%)
• Similarity: 70/147 - (47%)
• Gaps: 13/147 - (8%)

  Fly    24 FHAFFHE--------PPVWSVALPRNWQQIARWQEQEFAPPATVNKDGYKLTLDVKDYS--ELKV 78
            |..||.|        |.:.|...|...|.:.|............::|.:.:.||||.:|  :|.|
Human    23 FDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTV 87

  Fly    79 KVLDESVVLVEGKSEQQEAEQGGYSSRHFLRRFVLPEGYEADKVTSTLSSDGVLTISVPN-PPGV 142
            ||.|: .|.:.||..::: :..||.||.|.||:.||...:...::.:||:||:||...|. ..|:
Human    88 KVQDD-FVEIHGKHNERQ-DDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGL 150

  Fly   143 QETLKEREVTIEQTGEP 159
            ..|..||.:.:.:..:|
Human   151 DATHAERAIPVSREEKP 167

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp22	NP_001027114.1	metazoan_ACD	61..138	CDD:107247	29/78 (37%)
CRYAA	NP_000385.1	Crystallin	1..54	CDD:425732	8/30 (27%)
		ACD_alphaA-crystallin_HspB4	60..145	CDD:107245	29/86 (34%)