Protein Alignment Hsp22 and Cryab

DIOPT Version :10

• Sequence 1: NP_001027114.1
• Gene: Hsp22 / 3772576
• FlyBaseID: FBgn0001223
• Length: 174
• Species: Drosophila melanogaster
• Sequence 2: NP_034094.1
• Gene: Cryab / 12955
• MGIID: 88516
• Length: 175
• Species: Mus musculus
• Alignment Length: 315
• Identity: 54/315 - (17%)
• Similarity: 100/315 - (31%)
• Gaps: 87/315 - (27%)

  Fly  1376 VKFSVTCYFAT----QFDTLR----KTCCPSEVDFVRSLSRCQRWSAQGGKSNVYFAKSLDERFI 1432
            :.|.:.|::.:    :.:|.|    |..|.:..:..|.|.|         :.|:...|..:.|:.
Mouse     6 IHFLIVCFYESLMGEKGETYRVRLLKAPCGNSKEVSRWLCR---------RMNLPCEKGPEGRYD 61

  Fly  1433 IKQVVKTELDSFEDFAP------------------EYFKYLKESLSSGSPTCLAK------ILGI 1473
            .:.:.:|:..:|..|.|                  ....:....||:|:...|..      :..:
Mouse    62 FESMAETDRRAFSKFNPAAKQPAENAALAPLRDGVSLIDHCSGQLSTGAQVHLEVTSRTPFVNRV 126

  Fly  1474 YQVS-IKHPKGGKE------TKMDLMVMENLFYNRRISRI----------------YDLKGSARS 1515
            |..| :..|.|.::      |:...::.:|..:.|..||:                ..:|..::.
Mouse   127 YPTSDLWVPAGARDRPQTPPTRPSALIYDNSEHKRWNSRMRPEAALKAKLEGWTNAQSIKQPSQD 191

  Fly  1516 RYNPNTSGADKVLLDMNLLETLRTEPIFLGSKAKRSLERAIWND----------TNFLASVDVMD 1570
            .:..|......||.|..  .|...:.|:. |..:|..|...|:.          ::.....|.:.
Mouse   192 SHEINADPDPSVLFDSK--ATAAQQYIYT-SATQRGYEDVAWDSKLPPRHEPPISSLEKMADPVS 253

  Fly  1571 YSLLVGFDEERKELVLGIIDFMRQYTWDKHLETWVKASGILGGPKNASPTIVSPK 1625
            ...::.....|.||...|...     |.||     :..|.....|..|.|...||
Mouse   254 QCFVLKRYHSRPELWQAIGSH-----WSKH-----QLRGTFNPKKPISFTSSCPK 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp22	NP_001027114.1	metazoan_ACD	61..138	CDD:107247
Cryab	NP_034094.1	Crystallin	1..55	CDD:425732	10/57 (18%)
		ACD_alphaB-crystallin_HspB5	67..150	CDD:107246	13/82 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	145..175		5/29 (17%)