Protein Alignment Hsp22 and HSPB6

DIOPT Version :10

• Sequence 1: NP_001027114.1
• Gene: Hsp22 / 3772576
• FlyBaseID: FBgn0001223
• Length: 174
• Species: Drosophila melanogaster
• Sequence 2: NP_653218.1
• Gene: HSPB6 / 126393
• HGNCID: 26511
• Length: 160
• Species: Homo sapiens
• Alignment Length: 137
• Identity: 46/137 - (33%)
• Similarity: 66/137 - (48%)
• Gaps: 28/137 - (20%)

  Fly    11 AEEMARMPRLSSPFHAFFHEPPVWSVALPRNWQQIARWQEQEFAPPATVNKDGYKLTLDVKDYS- 74
            ||..|..|...:|:  :...|   |||||     :|:         ...:...:.:.||||.:|
Human    40 AELAALCPTTLAPY--YLRAP---SVALP-----VAQ---------VPTDPGHFSVLLDVKHFSP 85

  Fly    75 -ELKVKVLDESVVLVEGKSEQQEAEQGGYSSRHFLRRFVLPEGYEADKVTSTLSSDGVLTI---- 134
             |:.|||:.|.|. |..:.|::..|. |:.:|.|.||:.||.|.:...|||.||.:|||:|
Human    86 EEIAVKVVGEHVE-VHARHEERPDEH-GFVAREFHRRYRLPPGVDPAAVTSALSPEGVLSIQAAP 148

  Fly   135 -SVPNPP 140
             |...||
Human   149 ASAQAPP 155

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp22	NP_001027114.1	metazoan_ACD	61..138	CDD:107247	32/83 (39%)
HSPB6	NP_653218.1	Involved in stabilization of the HSPB1:HSBP6 heterodimer. /evidence=ECO:0000269|PubMed:27717639	1..72		12/50 (24%)
		Crystallin	3..62	CDD:425732	8/26 (31%)
		ACD_HspB4-5-6	66..144	CDD:107233	30/88 (34%)