DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tyler and Slc25a39

DIOPT Version :10

Sequence 1:NP_608327.2 Gene:Tyler / 3772349 FlyBaseID:FBgn0031038 Length:441 Species:Drosophila melanogaster
Sequence 2:NP_080818.1 Gene:Slc25a39 / 68066 MGIID:1196386 Length:359 Species:Mus musculus


Alignment Length:412 Identity:133/412 - (32%)
Similarity:197/412 - (47%) Gaps:93/412 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 IKPMQQVVSALVGGLITTFVVTPLEVVKTRVQTQH--AIRQRPTVSKL----------------- 88
            |.|:||:|::..|.::|:..:|||:|||.|:|:|.  |..:..|.|:.                 
Mouse     9 ISPLQQMVASGAGAVVTSLFMTPLDVVKVRLQSQRPSATSELTTPSRFWSLSYTKSSSALQSPGK 73

  Fly    89 CYVYHNGLM--THVCRSSDICVPKPGRDPQNLRPLRGAMDAFVKIVCTSGFSGLWAGLSPTLVSA 151
            |.:|.||::  .::|.:...|... .:||..   ..|.:|||||||...|...||:||..|||..
Mouse    74 CLLYCNGVLEPLYLCPNGTRCATW-FQDPTR---FTGTLDAFVKIVRHEGTRTLWSGLPATLVMT 134

  Fly   152 LPSTIIYFLTYEYIKNSLSHIYLVSQKFEESGMKDQVPGADGGDPLDQATRGINVSATAPVSTAS 216
            :|:|.|||..|:.:|     .:|..|..                                  |:.
Mouse   135 VPATAIYFTAYDQLK-----AFLCGQSL----------------------------------TSD 160

  Fly   217 LPYYVPMASGICSRTIVVTAITPIEMVRIKMQSEYMTYAELWRVLRSLIRQHGILGLWRGWPPTV 281
            |  |.||.:|..:|...||.::|:|:||.|:|:::::|.||...:::.:.|.|...||.||.||.
Mouse   161 L--YAPMVAGALARMGTVTVVSPLELVRTKLQAQHVSYRELASSVQAAVTQGGWRSLWLGWGPTA 223

  Fly   282 MRDAPFSGTYWAVYEAIKRAFSVTEP----TFLFSFLTGAISGAVATFVTMPFDLITTHTQIELG 342
            :||.|||..||..||.:|...|...|    :...||:.|.|||.||..:|:|||::.|..|:.| 
Mouse   224 LRDVPFSALYWFNYELVKSWLSGLRPKDQTSVGISFVAGGISGMVAATLTLPFDVVKTQRQMSL- 287

  Fly   343 QDVLYEEIGAGTGAGTGTGAGARPKTPQSAVANSRPSVLSRMRQIYRLQGVRGLYVGVMPRMLRV 407
                            |.....|.|.|:.      .|....:|:|....|.|||:.|.:||:::.
Mouse   288 ----------------GAVEAVRVKPPRV------DSTWLLLRRIRAESGTRGLFAGFLPRIIKA 330

  Fly   408 VPACAIMISTFEYSKSFFFHYN 429
            .|:|||||||:|:.||||...|
Mouse   331 APSCAIMISTYEFGKSFFQRLN 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TylerNP_608327.2 Mito_carr 41..171 CDD:395101 50/148 (34%)
Mito_carr 216..303 CDD:395101 35/86 (41%)
Mito_carr 306..429 CDD:395101 43/126 (34%)
Slc25a39NP_080818.1 Mito_carr 9..152 CDD:395101 50/151 (33%)
Solcar 1 9..151 50/150 (33%)
Solcar 2 159..243 35/85 (41%)
Mito_carr 161..246 CDD:395101 35/86 (41%)
Mito_carr 251..350 CDD:395101 42/121 (35%)
Solcar 3 253..347 39/116 (34%)

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