Protein Alignment Tyler and Slc25a39

DIOPT Version :8

• Sequence 1: NP_608327.2
• Gene: Tyler / 3772349
• FlyBaseID: FBgn0031038
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_080818.1
• Gene: Slc25a39 / 68066
• MGIID: 1196386
• Length: 359
• Species: Mus musculus
• Alignment Length: 412
• Identity: 133/413 (32%)
• Similarity: 197/413 (48%)
• Gaps: 93/413 (23%)

  Fly    43 IKPMQQVVSALVGGLITTFVVTPLEVVKTRVQTQH--AIRQRPTVSKL----------------- 88
            |.|:||:|::..|.::|:..:|||:|||.|:|:|.  |..:..|.|:.
Mouse     9 ISPLQQMVASGAGAVVTSLFMTPLDVVKVRLQSQRPSATSELTTPSRFWSLSYTKSSSALQSPGK 73

  Fly    89 CYVYHNGLM--THVCRSSDICVPKPGRDPQNLRPLRGAMDAFVKIVCTSGFSGLWAGLSPTLVSA 151
            |.:|.||::  .::|.:...|... .:||..   ..|.:|||||||...|...||:||..|||..
Mouse    74 CLLYCNGVLEPLYLCPNGTRCATW-FQDPTR---FTGTLDAFVKIVRHEGTRTLWSGLPATLVMT 134

  Fly   152 LPSTIIYFLTYEYIKNSLSHIYLVSQKFEESGMKDQVPGADGGDPLDQATRGINVSATAPVSTAS 216
            :|:|.|||..|:.:|     .:|..|..                                  |:.
Mouse   135 VPATAIYFTAYDQLK-----AFLCGQSL----------------------------------TSD 160

  Fly   217 LPYYVPMASGICSRTIVVTAITPIEMVRIKMQSEYMTYAELWRVLRSLIRQHGILGLWRGWPPTV 281
            |  |.||.:|..:|...||.::|:|:||.|:|:::::|.||...:::.:.|.|...||.||.||.
Mouse   161 L--YAPMVAGALARMGTVTVVSPLELVRTKLQAQHVSYRELASSVQAAVTQGGWRSLWLGWGPTA 223

  Fly   282 MRDAPFSGTYWAVYEAIKRAFSVTEP----TFLFSFLTGAISGAVATFVTMPFDLITTHTQIELG 342
            :||.|||..||..||.:|...|...|    :...||:.|.|||.||..:|:|||::.|..|:.|
Mouse   224 LRDVPFSALYWFNYELVKSWLSGLRPKDQTSVGISFVAGGISGMVAATLTLPFDVVKTQRQMSL- 287

  Fly   343 QDVLYEEIGAGTGAGTGTGAGARPKTPQSAVANSRPSVLSRMRQIYRLQGVRGLYVGVMPRMLRV 407
                            |.....|.|.|:.      .|....:|:|....|.|||:.|.:||:::.
Mouse   288 ----------------GAVEAVRVKPPRV------DSTWLLLRRIRAESGTRGLFAGFLPRIIKA 330

  Fly   408 VPACAIMISTFEYSKSFFFHYN 429
            .|:|||||||:|:.||||...|
Mouse   331 APSCAIMISTYEFGKSFFQRLN 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tyler	NP_608327.2	Mito_carr	41..171	CDD:278578	50/149 (34%)
		Mito_carr	216..302	CDD:278578	35/86 (41%)
		Mito_carr	306..429	CDD:278578	43/127 (34%)
Slc25a39	NP_080818.1	Mito_carr	9..152	CDD:278578	50/152 (33%)
		Solcar 1	9..151		50/151 (33%)
		Solcar 2	159..243		35/86 (41%)
		Mito_carr	161..246	CDD:278578	36/87 (41%)
		Mito_carr	251..350	CDD:278578	42/122 (34%)
		Solcar 3	253..347		40/117 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG0761
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0001348
OrthoInspector	1	1.000				T130986
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR45760
Phylome	1	0.910		0.800	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
	7	6.870