Protein Alignment Tyler and mtm1

DIOPT Version :10

• Sequence 1: NP_608327.2
• Gene: Tyler / 3772349
• FlyBaseID: FBgn0031038
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_595818.1
• Gene: mtm1 / 2541312
• PomBaseID: SPBP23A10.06
• Length: 335
• Species: Schizosaccharomyces pombe
• Alignment Length: 440
• Identity: 124/440 - (28%)
• Similarity: 190/440 - (43%)
• Gaps: 135/440 - (30%)

  Fly     9 MENGGEEEGCRLECKEMDPLRLTTLILSADPRYRIKPMQQVVSALVGGLITTFVVTPLEVVKTRV 73
            |:.|...||...:           |.::|:|  .:||:.:::||.||.:|||..||||:|||||:
pombe     1 MQIGAATEGVEAD-----------LSVNAEP--DVKPIAKMLSACVGSVITTLTVTPLDVVKTRL 52

  Fly    74 QTQHAIRQRPTVSKLCYVYHNGLMTHVCRSSDICVPKPGRDPQNLRPLRGAMDAFVKIVCTSGFS 138
            |:: :|.|..:             |....|:.|.    |:.....:||.|.:....:|....|..
pombe    53 QSE-SISQYSS-------------TQPISSAKIL----GKGRPAPKPLGGPVSGLYQIARHEGVR 99

  Fly   139 GLWAGLSPTLVSALPSTIIYFLTYEYIKNSLSHIYLVSQKFEESGMKDQVPGADGGDPLDQATRG 203
            .||.||.|:|...||:..:.||.||    .|..:|                 :|.|.|
pombe   100 SLWRGLVPSLTMLLPANTVQFLGYE----QLLPLY-----------------SDWGFP------- 136

  Fly   204 INVSATAPVSTASLPYYVPMASGICSRTIVVTAITPIEMVRIKMQSEYMTYA---------ELWR 259
                |.|.::.||            :|||..|.::|||:.|.::|:....|.         |::.
pombe   137 ----AAAAIAGAS------------ARTISATIVSPIELFRTRVQAVGGHYPPGHAREIANEVFD 185

  Fly   260 VLRSLIRQHGILGLWRGWPPTVMRDAPFSGTYWAVYEAIK---------RAFSVTEPT--FLFSF 313
            .|:.:|.|.|||.||.|...|:.||.|||..||..||.|:         :|||.::.|  ...:|
pombe   186 GLKLMIHQKGILNLWSGVSVTLWRDVPFSAFYWWSYERIRLFLLGHPSLQAFSSSQSTKDLYINF 250

  Fly   314 LTGAISGAVATFVTMPFDLITTHTQIELGQDVLYEEIGAGTGAGTGTGAGARPKTPQSAVANSRP 378
            ::|.|||.:||.:|.|||:..|..|:                                     ..
pombe   251 VSGGISGTLATLLTQPFDVSKTAKQV-------------------------------------HG 278

  Fly   379 SVLSR---MRQIYRLQGVRGLYVGVMPRMLRVVPACAIMISTFEYSKSFF 425
            ..|:|   |..:::..|.:.|:.|.:||.::|.|:||||||::..:|.:|
pombe   279 HTLTRGQFMLTLWKRGGPKALWKGTLPRCVKVAPSCAIMISSYHLTKKYF 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tyler	NP_608327.2	Mito_carr	41..171	CDD:395101	43/129 (33%)
		Mito_carr	216..303	CDD:395101	33/104 (32%)
		Mito_carr	306..429	CDD:395101	32/125 (26%)
mtm1	NP_595818.1	Mito_carr	21..132	CDD:395101	44/149 (30%)
		Mito_carr	148..231	CDD:395101	30/82 (37%)
		Mito_carr	242..331	CDD:395101	32/124 (26%)