Protein Alignment mi and mi

DIOPT Version :10

• Sequence 1: NP_611803.1
• Gene: mi / 37723
• FlyBaseID: FBgn0261786
• Length: 941
• Species: Drosophila melanogaster
• Sequence 2: XP_313994.5
• Gene: mi / 1274791
• VectorBaseID: AGAMI1_010999
• Length: 972
• Species: Anopheles gambiae
• Alignment Length: 1103
• Identity: 345/1103 - (31%)
• Similarity: 484/1103 - (43%)
• Gaps: 311/1103 - (28%)

  Fly     9 NNSYESEPSTGSGSSLSENNESHISDEDHMNLPYLMKPKALSSQPIKETPTPPNPKTGSQESQFL 73
            |||.:..|:..||   .|:|.:                         |||....| :|.|.|.
Mosquito    10 NNSLDGMPTPISG---CESNSA-------------------------ETPLDVMP-SGEQCSI-- 43

  Fly    74 GFGDSPYGQVNKRLYGSQLQNLKLPEVEPPAVRRPSPGKIVFPRFYDTLIEENSCNAVDMAVSVA 138
               |........:..||. |..:||.:                     |:.::||||||..:.|.
Mosquito    44 ---DQQSNDCTTQRRGSS-QKKRLPGL---------------------LLSDDSCNAVDNMLGVD 83

  Fly   139 TTATTTTG------SLSFDGKIKSLTAKP------------EIQDKPGPSNATNPRLSN------ 179
            ...|....      .|||:||||.|||:.            |...|......|:.|.|:
Mosquito    84 EKPTCKNADPAGNLDLSFNGKIKPLTAESLAVIRTVAADTVERSTKDEAELETDARKSSDDSRIR 148

  Fly   180 --------VLETSLNTSQQKFNNERSPDLFADSDDEAD--------NDEQPEKEPPTRLED---- 224
                    .|.|..|.|...:|||:|||||||.|::.|        ||::..:....|..|
Mosquito   149 DEKLNESFELLTKENNSLSHYNNEKSPDLFADDDEDDDENDDDDDGNDDEERQNASERNGDGGGQ 213

  Fly   225 --LPEVLEESQCTSDARARSSLNAPTESSFVDEQTMDLSSTQLNANDPRSHFLENCRRERELYRR 287
              ..:.|..||..:...:...:.:..||| ||                        |.:|.|.:|
Mosquito   214 GECEDYLHRSQARTSGASIKEMESANESS-VD------------------------RTDRILLKR 253

  Fly   288 IRRCLQGVRPPPSVTAPDVDVIKMVLSMKSNVLNFLSKDS--PPSTPRIEDS--GISE------- 341
            ::..|.|:.|||::|..|:|:..|:...::||..:|....  ..:|..::||  |:||
Mosquito   254 MQMSLAGIPPPPALTYSDIDIGTMLTIYRNNVEPWLVTHGFRTGTTKPLDDSAAGVSEPGEKLQQ 318

  Fly   342 TTSLFRPSHSLSEAQNMGWRDVLGVRHHGLSYNLNKAAEQNEYLSMSVVDRYVGVETATSYVRS- 405
            ...|.:|:|:..|...:.|.::...|.|||.||.:...|..|.|.:..::||:..||:.|:..:
Mosquito   319 QPCLMKPTHTTDELAALKWPELTHHRAHGLHYNRSGVTETIELLGLKYIERYISAETSCSFNMTV 383

  Fly   406 -PSSAKKRNMRMKMLTQSPGNRLSHLAKRRAIFSSANLATNS-QKLNSSI--------------- 453
             .|||||||.|:|:|.||||.||||||:|||.|||.:|..|| .|...||
Mosquito   384 LQSSAKKRNQRLKLLNQSPGRRLSHLARRRATFSSESLLNNSGSKGGGSIVSAGKGTIDAGVLRR 448

  Fly   454 --------GPQIMLDKKKVRNKRK---ATPKRKTPGSKKK-ARKTPSSSARK-RLYRTDL----- 500
                    ..|::||.||..|:||   .||||:|||.||. .|:||.|||:| .|.||:.
Mosquito   449 LNPHRVCNNRQVLLDPKKSDNRRKNKIKTPKRRTPGGKKSPRRRTPGSSAKKLSLLRTNAAGGKS 513

  Fly   501 ---IKPGPSRETSKRALFQSP------------------AKTLQQQQLMPPKPLFKPEIANRVER 544
               :....:||:||||||.||                  :|.|:       :.||...   ||.:
Mosquito   514 CSQVHVPATRESSKRALFLSPQNGGTSSATSRNDRAGSNSKQLE-------RSLFSDA---RVLK 568

  Fly   545 SKRALFSP------DHQG---------SSNQLESILKRKRNACDDDEDSADLASQSSKLFRAESS 594
            |||:||||      :.:|         ||:.:.:  ||:|::..|..::.....::.|:.|.|::
Mosquito   569 SKRSLFSPVRGAATEDKGNPPAASAASSSSTVTN--KRRRSSITDSGETDRSGERTEKIRRTEAA 631

  Fly   595 G--PSGLTPRALKI-KSQSFCIGAGSSTAGVQLKLAQHAAATPGQTRLSLGLSGSSSNLVNPASF 656
            |  ...||||:||. :|:|||:|..|.|.                         .|::.|..|..
Mosquito   632 GLTEEDLTPRSLKFARSRSFCVGVQSMTL-------------------------PSASAVECAPI 671

  Fly   657 ASGTPLASKLHRAHSEMSATPNSSMTDNQRKKLLWAVSQALQEKKITPKHEQFRQHAADLTRIVK 721
            ..|.||........||....|.:.:|:|.:||||||||||||.|:||.|||.|:|||:.|.|:||
Mosquito   672 VGGRPLIRASSDICSEDGPRPVAVLTENHKKKLLWAVSQALQSKQITTKHELFKQHASILARVVK 736

  Fly   722 RIFQEFYLGHSSSNSETLLRLAKKFAFSVIAGKNADDVYLQARSQECEAKRLSSTRLSGYIGPEE 786
            |:|.||.....||.||.:|:||.|..:.||.||:..::|.:.:::...|:.:.  :|.|||.|||
Mosquito   737 RLFLEFNDQTISSTSEKMLKLANKHVYEVIQGKSEHEIYFREKTRLSNARNMQ--KLQGYIAPEE 799

  Fly   787 FAQRKL--LLSQTSV-VGSAAGSARSLHNIFGSENSI----DSF--GLSQMSLPTNACSETQSSI 842
            :..|:|  ..|.||. ..|....:.|....|.|::||    .||  ||||:|.|....
Mosquito   800 YELRRLKRTASTTSFDATSPFDCSLSASQSFLSQSSILSQGSSFGGGLSQLSQPNGFM------- 857

  Fly   843 VDRISEDLFCKERQPIRPNASLQNSSSKSNLG---------GLALRENMDCEAR-RSAQKN--FT 895
              |......|.....::|.||..:.::...||         ..|||||:|.|.| ||.:|.  |:
Mosquito   858 --RGGAGAGCAAVGHLKPAASTGSVNTVGLLGASIVGSLSSSTALRENVDSELRQRSTKKQLLFS 920

  Fly   896 GKDQQNISPY-----------FGGGGSNSSARKFQMPPVGNSNHSGG-------KAKRQISFD 940
            ||||:|:|||           .||||:           |||....||       ||||||||:
Mosquito   921 GKDQKNLSPYRMDKSLSLIGGVGGGGN-----------VGNKLLVGGAANSSIMKAKRQISFE 972