DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sxl and Rbms2

DIOPT Version :10

Sequence 1:NP_001259303.1 Gene:Sxl / 3772180 FlyBaseID:FBgn0264270 Length:722 Species:Drosophila melanogaster
Sequence 2:NP_001416152.1 Gene:Rbms2 / 56516 MGIID:1861776 Length:409 Species:Mus musculus


Alignment Length:486 Identity:122/486 - (25%)
Similarity:177/486 - (36%) Gaps:126/486 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    49 SSSSRRGYNDFPGCGGSGGNGGSANNLGGGNMCHLPPMASNNSLNNLCGLSLGSGGSDDLMNDPR 113
            |.:||.|.:.|      |.|..:........|.  ||...|::.|:..|...||||:|.|     
Mouse     4 SVTSRPGISTF------GYNKNNKKLYVAQQMA--PPSPRNSTPNSSGGGGGGSGGNDQL----- 55

  Fly   114 ASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKVL 178
             |.|||.:..|....||::|..|.:..|.|.:.:.:.|..|....||.||||.|...:|:|:..|
Mouse    56 -SKTNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSSAQKAVTAL 119

  Fly   179 NGITVRNKRLKVSYARPGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRP 243
            ....|:.:..|.....|       ||||::|||.::.:.:|:.:...:|.::...|||| .:|..
Mouse   120 KASGVQAQMAKQQEQDP-------TNLYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGAS 176

  Fly   244 RGVAFVRYNKREEAQEAISALNN---VIPEG---GSQPLSVRLAEEHGKAKAAHFMSQMGVVPAN 302
            |||.|.|....|:.:..|:..|.   ..|.|   .|.||..:.|:...|.:    .||...|...
Mouse   177 RGVGFARMESTEKCEAIITHFNGKYIKTPPGVAAPSDPLLCKFADGGPKKR----QSQGRYVQNG 237

  Fly   303 VPPPPPQPPAHMAAAFNMMHRDGAMEKLRSLFDAICDAIFGLDSENFADLLDGLYRRKYHY---- 363
            ...|                |:|.|..:...:|..            |.|.:|.|...|..    
Mouse   238 RAWP----------------RNGDMGGMALTYDPT------------AALQNGFYAAPYSIAHSR 274

  Fly   364 --------PYLXLTPQQQQQLLQ----------HQQQALGFTSSSNNSIGNGNGNDNNMLLYHQQ 410
                    ||| ......|::.|          ..|..|.||..|.:.:  ..|.|:.:.|....
Mouse   275 MLAQSALAPYLPSPVSSYQRVTQTSPLQVPNPSWMQYQLYFTQPSGSVL--TPGMDHPLSLQPAS 337

  Fly   411 YHQQQTQQQRLGNVAAHNISPNGSNNNINTSNTNNINFNTIRQNGVAALH--YLQEQLQLQQP-- 471
            .....|||  ||::         |.|::.|.           ....||:|  |:.     |.|  
Mouse   338 MMGPLTQQ--LGHL---------SLNSLGTF-----------MPAAAAMHGAYIS-----QYPAV 375

  Fly   472 -------QDQQSQQQQPLTMPSSP----PFQ 491
                   ::...||.|....|.|.    |||
Mouse   376 PSSSVSAEESNGQQNQLAVEPPSDHGVYPFQ 406

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SxlNP_001259303.1 sex-lethal 16..297 CDD:273740 76/253 (30%)
Rbms2NP_001416152.1 None

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