DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sxl and Rbms2

DIOPT Version :10

Sequence 1:NP_001259303.1 Gene:Sxl / 3772180 FlyBaseID:FBgn0264270 Length:722 Species:Drosophila melanogaster
Sequence 2:XP_063119154.1 Gene:Rbms2 / 288771 RGDID:1304813 Length:405 Species:Rattus norvegicus


Alignment Length:513 Identity:118/513 - (23%)
Similarity:180/513 - (35%) Gaps:145/513 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    49 SSSSRRGYNDFPGCGGSGGNGGSANNLGGGNMCHLPPMASNNSLNNLCGLSLGSGGSDDLMNDPR 113
            |.:||.|.:.|      |.|..:........|.  ||...|.:.|:    |.||||:|.|     
  Rat     4 SVTSRPGISTF------GYNKNNKKLYVAQQMA--PPSPRNGTPNS----SSGSGGNDQL----- 51

  Fly   114 ASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKVL 178
             |.|||.:..|....||::|..|.:..|.|.:.:.:.|..|....||.||||.|...:|:|:..|
  Rat    52 -SKTNLYIRGLQPSTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSSAQKAVTAL 115

  Fly   179 NGITVRNKRLKVSYARPGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRP 243
            ....|:.:..|.....|       ||||::|||.::.:.:|:.:...:|.::...|||| .||..
  Rat   116 KASGVQAQMAKQQEQDP-------TNLYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TTGAS 172

  Fly   244 RGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEEHGKAKAAHFMSQMGVVPANVPPPPP 308
            |||.|.|....|:.:..|:                            ||..:....|..|..|..
  Rat   173 RGVGFARMESTEKCEAIIT----------------------------HFNGKYIKTPPGVAAPSD 209

  Fly   309 QPPAHMAAAFNMMHRDGAMEKLRSLFDAICDAIFGLDSENFADLLDGLYRRKYHYPYLXLTPQQQ 373
                                      ..:|         .|||  .|..:|           |.|
  Rat   210 --------------------------PLLC---------KFAD--GGPKKR-----------QNQ 226

  Fly   374 QQLLQHQQQALGFTSSSNNSIGNGNGNDNNMLLYHQQYHQQQTQQQRLGNVAAHNISPNGSNNNI 438
            .:.:|            |......||:...|.|.:......|                    |..
  Rat   227 GKFVQ------------NGRAWPRNGDMGGMALTYDPTTALQ--------------------NGF 259

  Fly   439 NTSNTNNINFNTIRQNGVAALHYLQEQLQLQQPQDQQSQQQQPLTMPSSPPFQQQSRQSHHNGSS 503
            .|:..:..:...:.|:.:|.  ||...:...|...|.|    |:.:|::...||||.....:||.
  Rat   260 YTAPYSLAHSRMLAQSALAP--YLPSPVSSYQRVTQTS----PVQVPNTSWMQQQSYLMQPSGSV 318

  Fly   504 STLG-NQLLAISNNNSFNNNSNQSNSFTGNYSNGSAFTSNGAISG---SNFPNNPTSS 557
            .|.| :..|::...:.....:.|....:.| |.|:...:..|:.|   |.:|..|:||
  Rat   319 LTPGMDHPLSLQPASMMGPLTQQLGHLSLN-SLGTFMPAAAAMQGTYISQYPAVPSSS 375

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SxlNP_001259303.1 sex-lethal 16..297 CDD:273740 69/247 (28%)
Rbms2XP_063119154.1 None

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