Protein Alignment Sxl and Pabpc4

DIOPT Version :10

• Sequence 1: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Sequence 2: NP_570951.2
• Gene: Pabpc4 / 230721
• MGIID: 2385206
• Length: 660
• Species: Mus musculus
• Alignment Length: 476
• Identity: 108/476 - (22%)
• Similarity: 174/476 - (36%)
• Gaps: 126/476 - (26%)

  Fly   117 TNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKVLNGI 181
            ||:.:....:::.|..|..||...|...:.::||| .:|.|.|:.||.:....|:.:|::.:||.
Mouse   191 TNVYIKNFGEEVDDGNLKELFSQFGKTLSVKVMRD-SSGKSKGFGFVSYEKHEDANKAVEEMNGK 254

  Fly   182 TVRNKRLKVSYARPGGE------------------SIKDTNLYVTNLPRTITDDQLDTIFGKYGS 228
            .:..|.:.|..|:...|                  ..:..|||:.||..||.|::|...|..:||
Mouse   255 EMSGKAIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRREFSPFGS 319

  Fly   229 IVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEEHGKAKAAHFM 293
            |....::.:  .||.:|..||.::..|||.:|::.:|..|.  ||:||.|.||:...:.| ||..
Mouse   320 ITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGRIV--GSKPLYVALAQRKEERK-AHLT 379

  Fly   294 SQMGVVPANVPPPPPQPPAHMAAAFNMMHRDGAMEKLRSLFDAICDAIFGLDSENFADLLDGLY- 357
            :|                        .|.|...|..|.:      .||.    ..|.....|.:
Mouse   380 NQ------------------------YMQRVAGMRALPA------SAIL----NQFQPAAGGYFV 410

  Fly   358 --------RRKYHYP----YLXLTPQQQQ----QLLQHQQQAL---GFTSSSNNSIGNGNGNDNN 403
                    |..|:.|    .:...|:.||    |..|....||   |...:..:....||...:.
Mouse   411 PAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSALRQSGPRPALRHLAPTGNAPASR 475

  Fly   404 MLLYHQQYHQQQTQQQRLGNVAAHNI---------SPNGSNNNINTSNTNNINFNTIRQNGVAAL 459
            .|         .|..||:|:.....:         :..|..::..:........|...:..|||.
Mouse   476 GL---------PTTAQRVGSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVPNLAPRAAVAAA 531

  Fly   460 -----------------HYLQEQLQLQQPQDQQSQQQQPLT---MPSSPPFQQQSR--------- 495
                             |...:.||..||. ...|.|:|||   :.::||.:|:..
Mouse   532 APRAVAPYKYASSVRSPHPAIQPLQAPQPA-VHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLI 595

  Fly   496 QSHHNGSSSTLGNQLLAISNN 516
            |:.|:..:..:...||.|.|:
Mouse   596 QTMHSNLAGKITGMLLEIDNS 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	sex-lethal	16..297	CDD:273740	58/197 (29%)
Pabpc4	NP_570951.2	PABP-1234	11..640	CDD:130689	108/476 (23%)