Protein Alignment Sxl and HNRNPR

DIOPT Version :10

• Sequence 1: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Sequence 2: XP_047280655.1
• Gene: HNRNPR / 10236
• HGNCID: 5047
• Length: 661
• Species: Homo sapiens
• Alignment Length: 345
• Identity: 72/345 - (20%)
• Similarity: 114/345 - (33%)
• Gaps: 125/345 - (36%)

  Fly   117 TNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKVLNG- 180
            |.:.|..:|:|:.:.||..||...|||...|:|.|..:|.:.||||:.|..:..:|.|:|:.:.
Human   190 TEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSY 254

  Fly   181 -----------ITVRNKRLKV--------------SYARPGG--ESIKDTNLY------------ 206
                       |:|.|.||.|              .:::..|  |.:.|..||
Human   255 EIRPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFSKVTGLTEGLVDVILYHQPDDKKKNRGF 319

  Fly   207 -----------------------------------------------------VTNLPRTITDDQ 218
                                                                 |.||..|:|::.
Human   320 CFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEI 384

  Fly   219 LDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEE 283
            |:..|.::|.:.:...|:|        .|||.:..|..|.:|:..:|....||  :.:.:.||:.
Human   385 LEKSFSEFGKLERVKKLKD--------YAFVHFEDRGAAVKAMDEMNGKEIEG--EEIEIVLAKP 439

  Fly   284 HGKAK----AAHFMSQMGVVPANVPPPPPQPPAHMAAAFNMMHRDGAMEKLRSLFDAICDAIFGL 344
            ..|.:    ||...|:..........|||:.|..:........|.|                :|.
Human   440 PDKKRKERQAARQASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGG----------------YGY 488

  Fly   345 --DSENFADLLDGLYRRKYH 362
              |...:.|..|..|...||
Human   489 PPDYYGYEDYYDDYYGYDYH 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	sex-lethal	16..297	CDD:273740	59/276 (21%)
HNRNPR	XP_047280655.1	NURR_hnRNPR	52..135	CDD:410955
		hnRNP-R-Q	131..656	CDD:273732	72/345 (21%)