DRSC/TRiP Functional Genomics Resources

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Protein Alignment Argl and ARG4

DIOPT Version :10

Sequence 1:NP_609257.3 Gene:Argl / 3771738 FlyBaseID:FBgn0032076 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_011882.1 Gene:ARG4 / 856411 SGDID:S000001060 Length:463 Species:Saccharomyces cerevisiae


Alignment Length:453 Identity:217/453 - (47%)
Similarity:304/453 - (67%) Gaps:3/453 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 KMWGGRFTEGPHEALHSLNNSLPYDSRLYADDLDASKAYAEALHRAGLINSAEADKLVKNLELLR 74
            |:||||||......:|..|.|||||.::|..||:.:|.|...|.:.||:...|..|:.:.|..::
Yeast     7 KLWGGRFTGETDPLMHLYNASLPYDYKMYKADLEGTKVYTAGLQKLGLLTETELAKIHEGLAEIK 71

  Fly    75 FDWIEGTVKILPGDEDVHTVNERLLVEITG-ELGQRLHTGRSRNDQVVTDMKLWLRKAIRETL-G 137
            .:|........|.|||:||.|||.|.|:.| ::..::|||||||||||||::::.|..:.:|| .
Yeast    72 KEWDADKFVRHPNDEDIHTANERRLGELIGRDIAGKVHTGRSRNDQVVTDLRIYCRDIVNDTLFP 136

  Fly   138 RLSGIIETATRQAELHLGVLMPGYTHLQRAQTVQFSHWLLSHAFALREDGQRLLELRDRANVLPL 202
            .|.|::|...::||..:.|||||||||||||.:::||||.|:|....||.:||.::..|.|..||
Yeast   137 ALKGLVEVLIKRAEGEIDVLMPGYTHLQRAQPIRWSHWLSSYATYFTEDYKRLGQILHRLNQSPL 201

  Fly   203 GSGALAGNPLGIDRLWLAERLGFSGVTANSMHAVGDRDFVVDFIYCCSMVSLHLSRLAEDLIIYS 267
            |:|||||:|.||||.:|||.|||:.|..||:.||.||||:|:.::..::...|:||.|||||||.
Yeast   202 GAGALAGHPYGIDREFLAEGLGFNSVIGNSLVAVSDRDFIVELMFWGTLFMNHISRFAEDLIIYC 266

  Fly   268 TKEFDFIKLADGFSSGSSLMPQKRNPDSLELIRGMAGVITANLTGIMMTIKGTPSTYNKDLQYDK 332
            |.||.||:|:|.:|:||||||||:|.|||||:||.:|.:..:|||.:|::||.||||:||:|.||
Yeast   267 TAEFGFIQLSDAYSTGSSLMPQKKNADSLELLRGKSGRVFGDLTGFLMSLKGIPSTYDKDMQEDK 331

  Fly   333 QFCFQSFDKLSQVLEVTDGVLQTIQVKQESMEAALSTDMLATDWAYYLVKKGVPFRQAHHIIGRV 397
            :..|.....:...:.:..||:.|:.|.:|.|||||:.||||||.|.|||:||||||:.|||.|..
Yeast   332 EPLFDCLTTVEHSMLIATGVISTLTVNKEKMEAALTMDMLATDLADYLVRKGVPFRETHHISGEC 396

  Fly   398 VSEAEKRGVD-ITDLPLGDLQKFSPLFGSDIVAVADYSNNVQQYNAIGGTASSSIVEQLRLLK 459
            |:.||:.|:. |..|.|...||....||.|:....::..:|::.:|.||||.|::::||..||
Yeast   397 VATAERLGLSGIDKLTLEQYQKIDSRFGQDLFETFNFEQSVERRDATGGTAKSAVLKQLDNLK 459

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ArglNP_609257.3 Argininosuccinate_lyase 30..461 CDD:176463 208/433 (48%)
ARG4NP_011882.1 argH 8..463 CDD:129918 216/452 (48%)

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