DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment yip3 and PUP1

DIOPT Version :9

Sequence 1:	NP_523819.2	Gene:	yip3 / 37683	FlyBaseID:	FBgn0040063	Length:	193	Species:	Drosophila melanogaster
Sequence 2:	NP_014800.3	Gene:	PUP1 / 854328	SGDID:	S000005683	Length:	261	Species:	Saccharomyces cerevisiae

Alignment Length:	183	Identity:	43/183 - (23%)
Similarity:	79/183 - (43%)	Gaps:	25/183 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 IVGLKSTNAVILATDSKEYE-----------MYLIDDRIYCCAPRSGIDRNIVLEV---SSKVAN 64
            |||:|..|.|::|.|::..:           ::.|..:|:|....:..|...|.::   :.::.:
Yeast    32 IVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHS 96

  Fly    65 LVRDRGQN-VTVSQVRDMFCEKYQTAESPNVMIAGQDSRGLHLFSMEC-GKSRMVMYGAKGRDKE 127
            |...|... |:..|:......|||......:::||.|..|.||||:.. |.:.:..|.:.|....
Yeast    97 LYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSL 161

  Fly   128 NIVDFLSKDWNDFINLSEAEQLARKALR---W------EHVEMCTIYRAKEIE 171
            ..:..|...|...:...||.:||..|::   |      .:|::|.:...|:.|
Yeast   162 AAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAE 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
yip3	NP_523819.2	Ntn_hydrolase	14..155	CDD:294319	38/156 (24%)
PUP1	NP_014800.3	proteasome_beta_type_7	30..219	CDD:239732	43/183 (23%)
PUP1	NP_014800.3	Pr_beta_C	223..257	CDD:403609
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910