Protein Alignment Klp59C and kif2c

DIOPT Version :10

• Sequence 1: NP_611759.1
• Gene: Klp59C / 37671
• FlyBaseID: FBgn0034824
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001006856.1
• Gene: kif2c / 448620
• XenbaseID: XB-GENE-961445
• Length: 734
• Species: Xenopus tropicalis
• Alignment Length: 682
• Identity: 296/682 - (43%)
• Similarity: 385/682 - (56%)
• Gaps: 122/682 - (17%)

  Fly    12 IRRSDGRVHLAEIIKLEGGDSKLITVEWPEGHTVRGKELPLELVVLMNPHIFDS----PRCSGG- 71
            |.||:|.:|.|.|..: ..|...:.|||.||...:|||:....|:.:||.:.|:    |.....
 Frog    17 IMRSNGVIHNASITSV-NMDRSSVNVEWKEGDANKGKEISFADVISVNPELLDAVLAPPNVKENM 80

  Fly    72 ----NAASANQ---TASISPRSMKQRIATGSLSP-----------------------------VL 100
                |..|.||   |.|..| :.|:.....||.|                             |.
 Frog    81 PPQRNVPSQNQKRKTISKIP-APKEVTTQNSLLPEYGAQSVLRERSTRMTAIHEALPSENEMEVE 144

  Fly   101 ATAPPRQQTA-------------------------------PPVREDE------VVHQAERMRKE 128
            :|..|.||.:                               ||||.::      :|.:.|:|:.:
 Frog   145 STVLPVQQNSIQVGRSRSTKASVAGELRSQPRISEIVEESLPPVRNNQARRKSNIVKEMEKMKNK 209

  Fly   129 RERRREAQARTRLDREQGKNEDPGNPNWEVARMIRLQREQMESQRVRSGTTNERINCHQIMVCVR 193
            ||.:|...:..|:.|.|  :.|...||||..:||:..|..|:..|:......|.   |:|.||||
 Frog   210 REEQRAQNSELRIKRAQ--DYDTSIPNWEFGKMIKDFRATMDCHRISMADPAEE---HRICVCVR 269

  Fly   194 KRPLRRKELADREQDVVSIPSKHTLVVHEPRKHVNLVKFLENHSFRFDYVFDEECSNATVYEFTA 258
            ||||.::||:.:|.|::|:|||:.::||||:..|:|.|:|||..|||||.|||..:|..||.|||
 Frog   270 KRPLNKQELSKKEIDIISVPSKNIVLVHEPKLKVDLTKYLENQPFRFDYSFDETATNEVVYRFTA 334

  Fly   259 RPLIKHIFDGGMATCFAYGQTGSGKTYTMGGQFPGRHQSSMDGIYAMAAKDVFSTLKTVPYNKLN 323
            |||::.||:||.||||||||||||||:||||.|.|:.|:...|:||.|::|||..|....|..|:
 Frog   335 RPLVQSIFEGGKATCFAYGQTGSGKTHTMGGDFSGKSQNVSKGVYAFASRDVFLLLDQPRYKHLD 399

  Fly   324 LKVYCSFFEIYGTRVFDLLMPGKPQLRVLEDRNQQVQVVGLTQNPVQNTAEVLDLLELGNSVRTS 388
            |.|:.:|||||..:|||||.. |.:||||||..|:||||||.:..|.:..:|..::|:|::.|||
 Frog   400 LDVFVTFFEIYNGKVFDLLNK-KAKLRVLEDAKQEVQVVGLLERQVTSADDVFKMIEVGSACRTS 463

  Fly   389 GHTSANSKSSRSHAVFQIVLRSAAGEKLHGKFSLIDLAGNERGADNSSADRQTRLEGSEINKSLL 453
            |.|.|||.||||||..||:||  .|.||||||||:||||||||||.:||||.||:||:|||:|||
 Frog   464 GQTFANSSSSRSHACLQIILR--RGSKLHGKFSLVDLAGNERGADTASADRITRMEGAEINRSLL 526

  Fly   454 VLKECIRALGRQSSHLPFRGSKLTQVLRDSFIGGKKVKTCMIAMISPCLHSVEHTLNTLRYADRV 518
            .|||||||||:..||.|||.|||||:|||||| |:..:||||||:||..:|.|:|||||||||||
 Frog   527 ALKECIRALGQNKSHTPFRESKLTQILRDSFI-GENSRTCMIAMLSPGFNSCEYTLNTLRYADRV 590

  Fly   519 KELSVESIPSKRMPDANLG-STSMSDIVCQSSTQRLFPCASSTSMPGGGNQAQQ----------- 571
            ||||.::..:.   |.||. .|..||             .|..|:  ||.|.|.
 Frog   591 KELSPQNAETN---DDNLQMETEDSD-------------GSHASI--GGLQLQDDFLLKDEELST 637

  Fly   572 HTNTAND-LNRSQKPTSKPTYPTSGQQLVQRK 602
            |.|:..| |||..:...|.....  ::||||:
 Frog   638 HINSFQDALNRVGELEEKAVEEL--RELVQRE 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp59C	NP_611759.1	KISc_KIF2_like	187..519	CDD:276818	206/331 (62%)
kif2c	NP_001006856.1	KISc_KIF2_like	263..591	CDD:276818	206/331 (62%)