Protein Alignment Klp59C and kif2a

DIOPT Version :10

• Sequence 1: NP_611759.1
• Gene: Klp59C / 37671
• FlyBaseID: FBgn0034824
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: XP_005166887.1
• Gene: kif2a / 447926
• ZFINID: ZDB-GENE-040912-111
• Length: 747
• Species: Danio rerio
• Alignment Length: 573
• Identity: 290/573 - (50%)
• Similarity: 361/573 - (63%)
• Gaps: 71/573 - (12%)

  Fly    12 IRRSDGRVHLAEIIKLEGGDSKLITVEWPEGHTVRGKELPLELVVLMNPHIFDSPRCSGGNAASA 76
            |:|||||:|.|.:..| ..|::.:||||.|....:|||:.||.:..:||.:......|.......
Zfish    16 IKRSDGRIHQAMVTSL-NEDNESVTVEWIENGDTKGKEIDLECIFSLNPDVAPEEEISLSPVTPP 79

  Fly    77 NQTASISPRSMK--------QRIATG------------------------------SLSPVLATA 103
            ..|    |.|:|        :.||.|                              ...|..|..
Zfish    80 PPT----PSSVKVNKIPKNRRTIAPGRSEIPSRDNRVGSTRARPAQQLQQQQQQQPQPQPESAPP 140

  Fly   104 PPRQQTAPPV-----------------REDEVVHQAERMRKERERRREAQARTRLDREQGKNEDP 151
            ||.||.:.|.                 |:...|.:.|:::::|||||..|...|..|.|  ..|.
Zfish   141 PPAQQPSQPTQSQTQSQLTQQQQQNARRKSNCVKEVEKLQEKRERRRLQQQELREKRAQ--EVDT 203

  Fly   152 GNPNWEVARMIRLQREQMESQRVRSGTTNERINCHQIMVCVRKRPLRRKELADREQDVVSIPSKH 216
            ..||:|:.:|||..|..::   .|..||.:.|..|:|.||||||||.:|||:.::.||::||||.
Zfish   204 TIPNYEILQMIRDFRGSLD---YRPLTTTDLIEEHRICVCVRKRPLNKKELSVKDLDVITIPSKD 265

  Fly   217 TLVVHEPRKHVNLVKFLENHSFRFDYVFDEECSNATVYEFTARPLIKHIFDGGMATCFAYGQTGS 281
            .::||||::.|:|.::|||.:|||||.||:..:|..||.||||||::.|||.|||||||||||||
Zfish   266 VVMVHEPKQKVDLTRYLENQTFRFDYAFDDSTTNEMVYRFTARPLVETIFDRGMATCFAYGQTGS 330

  Fly   282 GKTYTMGGQFPGRHQSSMDGIYAMAAKDVFSTLKTVPYNKLNLKVYCSFFEIYGTRVFDLLMPGK 346
            |||:||||.|.|::|....||||:||:|||..||...|.||:|:||.:|||||..:||||| ..|
Zfish   331 GKTHTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNYKKLDLQVYATFFEIYSGKVFDLL-NRK 394

  Fly   347 PQLRVLEDRNQQVQVVGLTQNPVQNTAEVLDLLELGNSVRTSGHTSANSKSSRSHAVFQIVLRSA 411
            .:||||||..||||||||.:..|:.|.:||.|:|:|||.||||.||||:.||||||||||:||..
Zfish   395 AKLRVLEDGKQQVQVVGLQEREVKCTEDVLKLIEIGNSCRTSGQTSANAHSSRSHAVFQIILRRK 459

  Fly   412 AGEKLHGKFSLIDLAGNERGADNSSADRQTRLEGSEINKSLLVLKECIRALGRQSSHLPFRGSKL 476
            .  |:|||||||||||||||||.|||||||||||:|||||||.||||||||||...|.|||.|||
Zfish   460 G--KMHGKFSLIDLAGNERGADTSSADRQTRLEGAEINKSLLALKECIRALGRNKPHTPFRASKL 522

  Fly   477 TQVLRDSFIGGKKVKTCMIAMISPCLHSVEHTLNTLRYADRVKE--LSVESIP 527
            ||||||||| |:..:|||||.|||.:.|.|:||||||||:||||  :|...||
Zfish   523 TQVLRDSFI-GENSRTCMIATISPGMASCENTLNTLRYANRVKEFGISPSDIP 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp59C	NP_611759.1	KISc_KIF2_like	187..519	CDD:276818	222/331 (67%)
kif2a	XP_005166887.1	KISc_KIF2_like	236..564	CDD:276818	222/331 (67%)