Protein Alignment Klp59C and neb

DIOPT Version :10

• Sequence 1: NP_611759.1
• Gene: Klp59C / 37671
• FlyBaseID: FBgn0034824
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Alignment Length: 577
• Identity: 163/577 - (28%)
• Similarity: 248/577 - (42%)
• Gaps: 136/577 - (23%)

  Fly   146 GKNEDPGNPNWEVARMIRLQREQ-MESQRVRSGTTNERINCHQIMVCVRKRPLRRKELADREQ-- 207
            |:.:.||......:|  ..:|:. |||....|..:|       ::|.||.|||...| ..|.|
  Fly    87 GRAKTPGTGKSSCSR--TKERDSLMESCLSVSEESN-------MIVAVRVRPLNALE-CTRGQVT 141

  Fly   208 DVVSIPSKHTLVVHEPRKHVNLVKFLENHSFRFDYVF---DEECSN----ATVYEFTARPLIKHI 265
            :||.:......:..:.....:....: .|.|.:|.|:   |.|..|    |.|:|.||||||...
  Fly   142 NVVQVHGNSNELTVQAGSSADASAGV-THFFSYDQVYYSCDPERKNFACQAKVFEGTARPLIDTA 205

  Fly   266 FDGGMATCFAYGQTGSGKTYTMGGQFPGRHQSSMD--------GIYAMAAKDVFSTLKTV-PYNK 321
            |:|..|..||||||||||:|:|.| ......:::|        ||......::|..::.| ...:
  Fly   206 FEGYNACLFAYGQTGSGKSYSMMG-IEALDDAALDGGPPHDEAGIIPRFCHELFRRIEAVKSQQQ 269

  Fly   322 LNLKVYCSFFEIYGTRVFDLL-------------------MPGKPQLRVLEDRNQQVQVVGLTQN 367
            |.::|..|:||||..::.|||                   ...:|.|:|.|.......||.|:.:
  Fly   270 LQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTPIQQQQQQQRPALKVREHPIFGPYVVDLSAH 334

  Fly   368 PVQNTAEVLDLLELGNSVRTSGHTSANSKSSRSHAVFQIVLR-------------------SAAG 413
            .|.:.:.:.:.|.:|||.|.:..|:.|.||||||::|.|||.                   |:..
  Fly   335 SVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSIFNIVLNLTDLSSDDGLSSDTDSSTASSLR 399

  Fly   414 EKLHGKFSLIDLAGNERGADNSSADRQTRLEGSEINKSLLVLKECIRAL--------------GR 464
            :....|.||:||||:||.:.:.|...:.| ||..||||||.|.:.|.||              |.
  Fly   400 QTRRSKISLVDLAGSERISVSGSNGERIR-EGVSINKSLLTLGKVIAALADSRKAIANGPLGSGT 463

  Fly   465 QSSHLPFRGSKLTQVLRDSFIGGKKVKTCMIAMISPCLHSVEHTLNTLRYA-------------- 515
            .|:.:|:|.|.||.:||:: :||.. ||.|:|.|||.....:.||.|||||
  Fly   464 PSTFVPYRESVLTWLLREN-LGGNS-KTVMLATISPASIHADETLATLRYACKARSIVNRVKVNE 526

  Fly   516 --------------DRVKELSVESIPSKRMPDANLGSTSMSDIVCQSSTQRLFPCASSTSMPGGG 566
                          ||:|.|..|....:|: ..|..:.....|:.::|       ...|.:..
  Fly   527 SPHDKIIRDLRAEVDRLKSLRNEYERQRRL-SGNSNNPVPRKIIIETS-------VDETEVEA-- 581

  Fly   567 NQAQQHTNTANDLNRSQKPTSKPTYPTSGQ-----QLVQRKG------SSQREASMM 612
             ..||......:|:|:||...:.......|     ::::|:|      :.|::|.::
  Fly   582 -LRQQLAERERELSRAQKSWMEKLKEAEDQRKSELRVLKRRGLALELTAEQKQACLV 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp59C	NP_611759.1	KISc_KIF2_like	187..519	CDD:276818	134/429 (31%)
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	133/418 (32%)
		SMC_N	514..>615	CDD:481474	17/111 (15%)
		FHA_KIF14	627..741	CDD:438759	2/11 (18%)