DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Klp59C and nod

DIOPT Version :9

Sequence 1:	NP_611759.1	Gene:	Klp59C / 37671	FlyBaseID:	FBgn0034824	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	NP_001285129.1	Gene:	nod / 32107	FlyBaseID:	FBgn0002948	Length:	666	Species:	Drosophila melanogaster

Alignment Length:	406	Identity:	120/406 - (29%)
Similarity:	189/406 - (46%)	Gaps:	44/406 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 IMVCVRKRPLRRKELADREQDVVSIP---SKHTLVVHEPRKHVNLVKFLENHSFRFDYVFDEECS 249
            :.:.||:.|. |:.|..||..||..|   ...:|:|             :.:.|.||:.|....|
  Fly     9 VRIAVREAPY-RQFLGRREPSVVQFPPWSDGKSLIV-------------DQNEFHFDHAFPATIS 59

  Fly   250 NATVYEFTARPLIKHIFDGGMATCFAYGQTGSGKTYTMGGQFPGRHQSSMDGIYAMAAKDVFSTL 314
            ...:|:....||:..:.:|...|..||||||:||:|:||...||.......||...|..|:|..:
  Fly    60 QDEMYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSMGMTPPGEILPEHLGILPRALGDIFERV 124

  Fly   315 KT-VPYNKLNLKVYCSFFEIYGTRVFDLLMPGKPQLRVLEDRNQQVQVVGLTQNPVQNTAEVLDL 378
            .. ...||..::||.||.|||..:.|||| ...|.:.::..|.|:     .|..|:.:.|::..:
  Fly   125 TARQENNKDAIQVYASFIEIYNEKPFDLL-GSTPHMPMVAARCQR-----CTCLPLHSQADLHHI 183

  Fly   379 LELGNSVRTSGHTSANSKSSRSHAVFQIVLRSAAGEKLHGKFSLIDLAGNERGADNSSADRQTRL 443
            ||||...|....|:.||.||||||:..|.::|   :..|.:.:::||||:| |...:..:...|.
  Fly   184 LELGTRNRRVRPTNMNSNSSRSHAIVTIHVKS---KTHHSRMNIVDLAGSE-GVRRTGHEGVARQ 244

  Fly   444 EGSEINKSLLVLKECIRALGRQSSHLPFRGSKLTQVLRDSFIGGKKVKTCMIAMISPCLHSVEHT 508
            ||..||..||.:.:.:.::....:.:|:|.|.||.||:.|......:  ..:|.|||....:..|
  Fly   245 EGVNINLGLLSINKVVMSMAAGHTVIPYRDSVLTTVLQASLTAQSYL--TFLACISPHQCDLSET 307

  Fly   509 LNTLRYADRVKELSVESIPSKRMPDANLGSTSMSDIVCQSSTQRLFPCASSTSMPGGGNQAQQHT 573
            |:|||:....|:|.:..:...|...:           ..:.|..:|..|..||.....|.|..::
  Fly   308 LSTLRFGTSAKKLRLNPMQVARQKQS-----------LAARTTHVFRQALCTSTAIKSNAANHNS 361

  Fly   574 NTANDLNRSQKPTSKP 589
            ..   :.:|:..|:||
  Fly   362 IV---VPKSKYSTTKP 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Klp59C	NP_611759.1	KISc_KIF2_like	187..519	CDD:276818	106/334 (32%)
Klp59C	NP_611759.1	Kinesin	193..520	CDD:278646	105/330 (32%)
nod	NP_001285129.1	KISc	8..325	CDD:214526	108/341 (32%)
		KISc	8..318	CDD:276812	106/334 (32%)
		ComEA	540..648	CDD:224472
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437799
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030