Protein Alignment Klp59C and Kif2c

DIOPT Version :10

• Sequence 1: NP_611759.1
• Gene: Klp59C / 37671
• FlyBaseID: FBgn0034824
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: XP_006238694.1
• Gene: Kif2c / 171529
• RGDID: 620239
• Length: 722
• Species: Rattus norvegicus
• Alignment Length: 683
• Identity: 299/683 - (43%)
• Similarity: 395/683 - (57%)
• Gaps: 116/683 - (16%)

  Fly     5 SIEQKIF------IRRSDGRVHLAEI--IKLEGGDSKLITVEWPEGHTVRGKELPLELVVLMNPH 61
            |:..::|      |:||:|.:|.|.|  :.||   ...::|||.||.|.:|||:.::.|..:||.
  Rat     3 SLHARLFPGLSINIQRSNGLIHSANISTVNLE---KSCVSVEWTEGGTTKGKEIDIDDVAAINPE 64

  Fly    62 IF--------DS---------------------PRCSGGNAASANQTASIS-------------- 83
            :.        ||                     |....|..:.:.:.:::|
  Rat    65 LVQLLPLRPKDSLPLQENVTIPKQKRKSVNSKIPGPKEGLRSRSTRISTVSEVRIPAQENEMEVE 129

  Fly    84 -PRSMKQR----IATG----SLS-----PVLATAPPRQQTAPPVREDE-------------VVHQ 121
             |.|...|    |.||    |.|     |:|..:...::.|...|...             :|.:
  Rat   130 LPVSTNSRKPFPIHTGHPRPSCSTVTELPLLMISEEAEEQAHSTRSTSSANPGNSVRRKSCIVKE 194

  Fly   122 AERMRKERERRREAQARTRLDREQGKNEDPGNPNWEVARMIRLQREQMESQRVRSGTTNERINCH 186
            .|:|:.:||.:|...:..|:.|.|  ..|...||||.||||:..|..|:...:   |..:.|..|
  Rat   195 MEKMKNKREEKRAQNSEIRIKRAQ--EYDNSFPNWEFARMIKEFRVTMDCNPL---TVTDPIEEH 254

  Fly   187 QIMVCVRKRPLRRKELADREQDVVSIPSKHTLVVHEPRKHVNLVKFLENHSFRFDYVFDEECSNA 251
            :|.||||||||.::|||.:|.||:|:|||..|:||||:..|:|.|:|||.:|.||:.|||..||.
  Rat   255 RICVCVRKRPLNKQELAKKEIDVISVPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNE 319

  Fly   252 TVYEFTARPLIKHIFDGGMATCFAYGQTGSGKTYTMGGQFPGRHQSSMDGIYAMAAKDVFSTLKT 316
            .||.||||||::.||:||.||||||||||||||:||||...|:.|::..||||||::||| .||.
  Rat   320 VVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGGDLSGKSQNASKGIYAMASRDVF-LLKN 383

  Fly   317 VP-YNKLNLKVYCSFFEIYGTRVFDLLMPGKPQLRVLEDRNQQVQVVGLTQNPVQNTAEVLDLLE 380
            .| |..|||:||.:|||||..:|||||.. |.:||||||..||||||||.:..|....:|:.::.
  Rat   384 QPRYRSLNLEVYVTFFEIYNGKVFDLLNK-KAKLRVLEDSKQQVQVVGLQEYLVTCADDVIKMIN 447

  Fly   381 LGNSVRTSGHTSANSKSSRSHAVFQIVLRSAAGEKLHGKFSLIDLAGNERGADNSSADRQTRLEG 445
            :|::.||||.|.|||.||||||.|||:||  |..:|||||||:||||||||||.||||||||:||
  Rat   448 MGSACRTSGQTFANSNSSRSHACFQILLR--AKGRLHGKFSLVDLAGNERGADTSSADRQTRMEG 510

  Fly   446 SEINKSLLVLKECIRALGRQSSHLPFRGSKLTQVLRDSFIGGKKVKTCMIAMISPCLHSVEHTLN 510
            :|||||||.|||||||||:..:|.|||.|||||||||||| |:..:|||||||||.:.|.|:|||
  Rat   511 AEINKSLLALKECIRALGQNKAHTPFRESKLTQVLRDSFI-GENSRTCMIAMISPGISSCEYTLN 574

  Fly   511 TLRYADRVKELSVESIPSKRMPDANLGSTSMSDIVCQSSTQRLFPCASSTSMPGGGNQAQQHTNT 575
            ||||||||||||..|.||             .:...|..|:.:...:...|:.  ||:.::.::.
  Rat   575 TLRYADRVKELSPHSGPS-------------GEQAVQMETEEMDASSHGASLT--GNEEEELSSQ 624

  Fly   576 ANDLNRSQKPTSKPTYPTSGQQLVQRKGSSQRE 608
            .:..|.:.         |..::|.:|.....||
  Rat   625 MSSFNEAM---------TQIRELEERAMEELRE 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp59C	NP_611759.1	KISc_KIF2_like	187..519	CDD:276818	217/332 (65%)
Kif2c	XP_006238694.1	KISc_KIF2_like	255..583	CDD:276818	217/332 (65%)