Protein Alignment Klp59C and kif2c

DIOPT Version :10

• Sequence 1: NP_611759.1
• Gene: Klp59C / 37671
• FlyBaseID: FBgn0034824
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: XP_005163529.1
• Gene: kif2c / 100136875
• ZFINID: ZDB-GENE-070912-298
• Length: 700
• Species: Danio rerio
• Alignment Length: 702
• Identity: 275/702 - (39%)
• Similarity: 373/702 - (53%)
• Gaps: 136/702 - (19%)

  Fly     1 MDKLSIEQKIFIRRSDGRVHLAEIIKLEGGDSKLITVEWPEGHTVRGKELPL--------ELVVL 57
            :.||.|...:.|.|||||:|.| |:|........:.|||.|....:|||:.:        :|:..
Zfish     5 LSKLLIGLAVNISRSDGRIHSA-IVKTANVSKSTVNVEWAEHGMTKGKEVDMNELNHLNSDLIQH 68

  Fly    58 MNPHIFDSPRCSGGNAASANQTASISPRSM---KQRIATGSLSPVLATAPP-------------- 105
            :.|...:.|..:.........|.|:....:   ..||.|.| .|.....|.
Zfish    69 LQPCHQEEPAPTPIPTPMTRMTKSVKASELPLRSSRIPTTS-EPAPRDCPSEEPASRRMTTRQTC 132

  Fly   106 --RQQTAPPV----REDEVVHQ------------------------------------------- 121
              ||...|||    ..|:|:.|
Zfish   133 LFRQPAPPPVVSASSADDVLSQNLPSSTIPKHSGYQRRLLSKPASPLLPSTEAICESEASKCAPM 197

  Fly   122 ---AERMRKERERRREAQARTRLDR-----EQGKNEDPGNPNWEVARMIRLQREQMESQRVRSGT 178
               :.||.:..|..:.|..|..:.:     ::||..:. |.:.:..:||...||.::...:   :
Zfish   198 GPPSHRMSQVSETNKVANKRLSIAKMPDAQKRGKFGET-NRSKQFYQMIEEYRETVQKVPM---S 258

  Fly   179 TNERINCHQIMVCVRKRPLRRKELADREQDVVSIPSKHTLVVHEPRKHVNLVKFLENHSFRFDYV 243
            .::.:..|:|.||||||||.:||||.:|.|||:||....|::|||::.|:|.|:|||.:|.|||.
Zfish   259 LSDPVKTHRICVCVRKRPLNKKELAKKEIDVVTIPGNGVLLLHEPKQKVDLTKYLENQTFHFDYS 323

  Fly   244 FDEECSNATVYEFTARPLIKHIFDGGMATCFAYGQTGSGKTYTMGGQFPGRHQSSMDGIYAMAAK 308
            |||:.:|..||.|||:||:|.||:|||||||||||||||||:||||.|.|:.|:|..||||:||:
Zfish   324 FDEDATNDLVYRFTAKPLVKTIFEGGMATCFAYGQTGSGKTHTMGGDFSGKSQNSSKGIYALAAQ 388

  Fly   309 DVFSTLKTVPYNKLNLKVYCSFFEIYGTRVFDLLMPGKPQLRVLEDRNQQVQVVGLTQNPVQNTA 373
            |||:.|:...|..::|..|.:|||||..:|||||.. |.:||||||..|||.||||.:.||....
Zfish   389 DVFTLLRQKRYVDMDLCPYVTFFEIYNGKVFDLLNK-KTKLRVLEDEKQQVNVVGLQEVPVSCVD 452

  Fly   374 EVLDLLELGNSVRTSGHTSANSKSSRSHAVFQIVLRSAAGEKLHGKFSLIDLAGNERGADNSSAD 438
            :|:.::|.|::.||||.|.||:.||||||:.|::||..  ..|:|||||:||||||||.|.||.|
Zfish   453 DVIKMIERGSACRTSGQTFANASSSRSHAILQVILRRR--NFLYGKFSLVDLAGNERGTDVSSND 515

  Fly   439 RQTRLEGSEINKSLLVLKECIRALGRQSSHLPFRGSKLTQVLRDSFIGGKKVKTCMIAMISPCLH 503
            |.|.:|.:|||:|||.||||||:||:.|.|:|||.|||||||||||| |:..:|||||||||.:.
Zfish   516 RHTIVETAEINRSLLALKECIRSLGQNSEHIPFRMSKLTQVLRDSFI-GENSRTCMIAMISPGMS 579

  Fly   504 SVEHTLNTLRYADRVKELSVESIPSKRMPDANLGSTSMSDIVCQSSTQRLFPCASSTSMPGGGNQ 568
            |.|:||||||||:|||||:               ..|..|.|...|...|
Zfish   580 SCEYTLNTLRYANRVKELN---------------GISKGDAVENGSKLEL--------------- 614

  Fly   569 AQQHTNTANDLNRSQKPTSKPTYPTSGQ--QLVQR-----KGSSQREASMML 613
                   :.:.|.|::.|..|.:....:  ::.:|     ||.|:...||.|
Zfish   615 -------SEEGNSSEEETVLPEFEAISRVSEMEERFYEELKGCSEVAKSMEL 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp59C	NP_611759.1	KISc_KIF2_like	187..519	CDD:276818	203/331 (61%)
kif2c	XP_005163529.1	KISc_KIF2_like	267..595	CDD:276818	203/331 (61%)