Protein Alignment CG3700 and PRSS3

DIOPT Version :10

• Sequence 1: NP_611736.1
• Gene: CG3700 / 37640
• FlyBaseID: FBgn0034796
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_001184026.3
• Gene: PRSS3 / 5646
• HGNCID: 9486
• Length: 261
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 83/291 - (28%)
• Similarity: 119/291 - (40%)
• Gaps: 87/291 - (29%)

  Fly    98 STPF-----IVGGTKASGKEFPFMALI--GTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETD 155
            :.||     ||||........|:...:  |:|           .||||::..::|::||||.:|
Human    29 AVPFDDDDKIVGGYTCEENSLPYQVSLNSGSH-----------FCGGSLISEQWVVSAAHCYKT- 81

  Fly   156 ESKAERLDPNFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGY--DTEDEEQGFKNDIAL 218
                          :..|||||  :|....:...|.......:.||.|  ||.|      |||.|
Human    82 --------------RIQVRLGE--HNIKVLEGNEQFINAAKIIRHPKYNRDTLD------NDIML 124

  Fly   219 VELDRKAEFNDHVAAVCL---PPDSGNDVQQVTAAGWG----FTADGVKSSHLLKVNLQRFSDEV 276
            ::|...|..|..|:.:.|   ||.:|.   :...:|||    |.||              :.||:
Human   125 IKLSSPAVINARVSTISLPTTPPAAGT---ECLISGWGNTLSFGAD--------------YPDEL 172

  Fly   277 ------------CQKRLRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVS 329
                        |:......| |.:.||.|.:....|:|..|||||:.       |..|:.|:||
Human   173 KCLDAPVLTQAECKASYPGKI-TNSMFCVGFLEGGKDSCQRDSGGPVV-------CNGQLQGVVS 229

  Fly   330 YGLVCGSQGLPSVYTKVHLYTDWIESIVWGN 360
            :|..|..:..|.|||||:.|.|||:..:..|
Human   230 WGHGCAWKNRPGVYTKVYNYVDWIKDTIAAN 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	80/276 (29%)
PRSS3	NP_001184026.3	Tryp_SPc	38..256	CDD:238113	80/276 (29%)