Protein Alignment CG3700 and PRSS2

DIOPT Version :10

• Sequence 1: NP_611736.1
• Gene: CG3700 / 37640
• FlyBaseID: FBgn0034796
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 83/282 - (29%)
• Similarity: 121/282 - (42%)
• Gaps: 47/282 - (16%)

  Fly    94 SACQSTPF-----IVGGTKASGKEFPFMALI--GTHRPNKSKSDINWDCGGSVVHPKFVLTAAHC 151
            :|..:.||     ||||........|:...:  |.|           .||||::..::|::|.||
Human    11 AAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYH-----------FCGGSLISEQWVVSAGHC 64

  Fly   152 LETD-ESKAERLDPNFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKND 215
            .::. .||.......:.  :..|||||  :|....:...|.......:.||.|::    :...||
Human    65 YKSAINSKLSGRGCEYH--RIQVRLGE--HNIEVLEGNEQFINAAKIIRHPKYNS----RTLDND 121

  Fly   216 IALVELDRKAEFNDHVAAVCL---PPDSGNDVQQVTAAGWGFT----ADGVKSSHLLKVNLQRFS 273
            |.|::|...|..|..|:|:.|   ||.:|.   :...:|||.|    ||  ....|..::....|
Human   122 ILLIKLSSPAVINSRVSAISLPTAPPAAGT---ESLISGWGNTLSSGAD--YPDELQCLDAPVLS 181

  Fly   274 DEVCQKRLRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYGLVCGSQG 338
            ...|:......| |...||.|.:....|:|.||||||:.....|.       ||||:|..|..:.
Human   182 QAECEASYPGKI-TNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQ-------GIVSWGYGCAQKN 238

  Fly   339 LPSVYTKVHLYTDWIESIVWGN 360
            .|.|||||:.|.|||:..:..|
Human   239 RPGVYTKVYNYVDWIKDTIAAN 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	79/263 (30%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	79/263 (30%)