Protein Alignment CG3700 and PRSS1

DIOPT Version :10

• Sequence 1: NP_611736.1
• Gene: CG3700 / 37640
• FlyBaseID: FBgn0034796
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 79/279 - (28%)
• Similarity: 119/279 - (42%)
• Gaps: 55/279 - (19%)

  Fly    94 SACQSTPF-----IVGGTKASGKEFPFMALI--GTHRPNKSKSDINWDCGGSVVHPKFVLTAAHC 151
            :|..:.||     ||||........|:...:  |.|           .||||:::.::|::|.||
Human    11 AAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYH-----------FCGGSLINEQWVVSAGHC 64

  Fly   152 LETDESKAERLDPNFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDI 216
            .::               :..|||||  :|....:...|.......:.||.||    .:...|||
Human    65 YKS---------------RIQVRLGE--HNIEVLEGNEQFINAAKIIRHPQYD----RKTLNNDI 108

  Fly   217 ALVELDRKAEFNDHVAAVCL---PPDSGNDVQQVTAAGWGFTADGVKS--SHLLKVNLQRFSDEV 276
            .|::|..:|..|..|:.:.|   ||.:|.   :...:|||.||.....  ..|..::....|...
Human   109 MLIKLSSRAVINARVSTISLPTAPPATGT---KCLISGWGNTASSGADYPDELQCLDAPVLSQAK 170

  Fly   277 CQKRLRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYGLVCGSQGLPS 341
            |:......| |...||.|.:....|:|.||||||:.       |..|:.|:||:|..|..:..|.
Human   171 CEASYPGKI-TSNMFCVGFLEGGKDSCQGDSGGPVV-------CNGQLQGVVSWGDGCAQKNKPG 227

  Fly   342 VYTKVHLYTDWIESIVWGN 360
            |||||:.|..||::.:..|
Human   228 VYTKVYNYVKWIKNTIAAN 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	75/260 (29%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	73/258 (28%)