DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and Habp2

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001316864.1	Gene:	Habp2 / 226243	MGIID:	1196378	Length:	554	Species:	Mus musculus

Alignment Length:	404	Identity:	114/404 - (28%)
Similarity:	171/404 - (42%)	Gaps:	103/404 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 DNGTGECKELTPSDC-------------------PVIFYNQHLI---------------G-AEVK 53
            |...|:..|:.|.||                   |.:::|.||:               | ||..
Mouse   174 DQYKGKFCEIGPDDCYVGDGYSYRGKVSKTVNQNPCLYWNSHLLLQETYNMFMEDAETHGIAEHN 238

  Fly    54 YCD---------------------EFNDIVCCPIPLDHQN-----LKPAEQTRPFEKQCKQYNEV 92
            :|.                     |:.|:..||:| |..|     |:|..:...|| .|.:....
Mouse   239 FCRNPDGDHKPWCFVKVNSEKVKWEYCDVTVCPVP-DTPNPVESLLEPVMELPGFE-SCGKTEVA 301

  Fly    93 RSACQSTPFIVGGTKASGKEFPFMALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDES 157
            ..|.:.   |.||.|::..:.|:...:.|..|..:.......|||:::||.:|||||||  ||
Mouse   302 EHAVKR---IYGGFKSTAGKHPWQVSLQTSLPLTTSMPQGHFCGGALIHPCWVLTAAHC--TD-- 359

  Fly   158 KAERLDPNFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVEL- 221
                    .::....|.||:.|...|  ::..|.|||...:.:..|:..||..  .|||||::|
Mouse   360 --------INTKHLKVVLGDQDLKKT--ESHEQTFRVEKILKYSQYNERDEIP--HNDIALLKLK 412

  Fly   222 ---DRKAEFNDHVAAVCLPPDSGNDVQQVTAAGWGFTADGVKSSHLLKVNLQRFSDEVCQKRLRF 283
               ...|..:.:|..||||.|......:...:|||.|..|..|..||...::..::.:|..|..:
Mouse   413 PVGGHCALESRYVKTVCLPSDPFPSGTECHISGWGVTETGEGSRQLLDAKVKLIANPLCNSRQLY 477

  Fly   284 --SIDTRTQFCAGSMSSQ-ADTCNGDSGGPIFVQHPLYPCLKQ----VIGIVSYGLVCGSQGLPS 341
              :||. :..|||::... :|||.||||||:       .|.|.    |.||||:|..||.:  |.
Mouse   478 DHTIDD-SMICAGNLQKPGSDTCQGDSGGPL-------TCEKDGTYYVYGIVSWGQECGKK--PG 532

  Fly   342 VYTKVHLYTDWIES 355
            |||:|..:.:||::
Mouse   533 VYTQVTKFLNWIKT 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	87/265 (33%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	85/261 (33%)
Habp2	NP_001316864.1	EGF_CA	67..103	CDD:238011
		EGF_CA	150..182	CDD:238011	2/7 (29%)
		KR	187..271	CDD:238056	12/83 (14%)
		Tryp_SPc	308..547	CDD:238113	87/265 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4773
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960