Protein Alignment CycB and ccna2

DIOPT Version :10

• Sequence 1: NP_726244.1
• Gene: CycB / 37618
• FlyBaseID: FBgn0000405
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001006768.1
• Gene: ccna2 / 448454
• XenbaseID: XB-GENE-923016
• Length: 415
• Species: Xenopus tropicalis
• Alignment Length: 509
• Identity: 130/509 - (25%)
• Similarity: 220/509 - (43%)
• Gaps: 126/509 - (24%)

  Fly    16 ENFKQVQLKKLTVPSMEATTKRAALGDLQ--NRGISRPIAAKDAAQKDSKDLKLTDALRNAKARV 78
            ||.:.||.:|...|    ...|..||.||  :||.....|:|             .||:.|:|..
 Frog     9 ENQENVQPRKPLAP----VGGRTVLGVLQENHRGRQTLKASK-------------PALQQAQALS 56

  Fly    79 DSHWKKQPLGSTNGNGNGAVPPKVNEGGVSAFLRSNSVRNRVPTKT--TVEPTKVTVKSSSSENV 141
            .:|     || .|....|.||             :....::.||.|  ..||       ..:.|.
 Frog    57 VNH-----LG-VNDENYGKVP-------------AGKAASKQPTFTIHVDEP-------DCTNNR 95

  Fly   142 NEPTLKR--EDSNLSKKSLTKLRAALAKPVMGVSGIRR--EPVAVSRKEAETKKELPETKKDSLE 202
            .:|..|:  :|.||.:          ...|:|..|.|:  ||:.::.:
 Frog    96 RKPVHKKTVQDENLRQ----------LNSVLGSIGTRKPLEPIHIAME----------------- 133

  Fly   203 VKKDATRMPLIRGNSAVTTTTSTMPTTMSLSSKRLAGIEDIDANDKENLVL----VSEYVNDIYD 263
                             |:..|.|               |:...|:|..|:    |.:|..:|:.
 Frog   134 -----------------TSFGSPM---------------DVSLVDEEQKVVGCSNVPDYAKEIHT 166

  Fly   264 YLYQVELEQPIHKDHLAGQKEVSHKMRAVLIDWINEVHLQFHLAAETFQLAVAIIDRYLQVVKDT 328
            ||.::|::......::..|.:::..|||:|:||:.||..::.|..||..|||..|||:|..: ..
 Frog   167 YLREMEVKCKPKSGYMQKQPDITGNMRAILVDWLVEVGEEYKLQNETLYLAVNYIDRFLSSM-SV 230

  Fly   329 KRTYLQLVGVTALFIATKYEELFPPAIGDFVFITDDTYTARQIRQMELQIFKAIDCNLSRPLPIH 393
            .|..|||||..|:.:|:|:||::||.:.:||:|||||||.:|:.:||..:.|.:..:|:.|..:.
 Frog   231 LRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLKMEHLVLKVLSFDLAAPTILQ 295

  Fly   394 FLRRYSKAAGAEDEHHTMSKYFIELASVDYE-MATYRPSEIAAASLFLSLHLLNGNHRAGTGFND 457
            :|.:|.:......:..::|.:..||:.||.: ...|.||.:|||:..::.:.:          |:
 Frog   296 YLNQYFQIQPVSPKVESLSMFLGELSLVDADPFLRYLPSVVAAAAFVIANYTV----------NE 350

  Fly   458 RHWTPTLTFYSRYSAAHLRPITRLIAKLARDAPQAKLKAIYNKYQGSKFQKIAL 511
            |.|:.:|..|:.|:...|:|....:.:....|...:.:|:..||:..|...::|
 Frog   351 RTWSDSLVQYTGYALETLKPCILDLYQTYLSAASHQQQAVREKYKTQKNHCVSL 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycB	NP_726244.1	CYCLIN_CCNB1-like_rpt1	254..384	CDD:410211	51/129 (40%)
		CYCLIN_CCNB1-like_rpt2	389..509	CDD:410213	27/120 (23%)
ccna2	NP_001006768.1	Cyclin_N2	82..143	CDD:465146	19/126 (15%)
		CYCLIN_CCNA2_rpt1	157..287	CDD:410264	51/130 (39%)
		CYCLIN_CCNA2_rpt2	291..400	CDD:410267	27/118 (23%)