Protein Alignment CycB and CycB3

DIOPT Version :10

• Sequence 1: NP_726244.1
• Gene: CycB / 37618
• FlyBaseID: FBgn0000405
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_651303.2
• Gene: CycB3 / 42971
• FlyBaseID: FBgn0015625
• Length: 575
• Species: Drosophila melanogaster
• Alignment Length: 574
• Identity: 157/574 - (27%)
• Similarity: 240/574 - (41%)
• Gaps: 121/574 - (21%)

  Fly    32 EATTKRA-----------------ALGDLQNRGISRPIAA-------------KDAAQKDSKDLK 66
            :|||:.|                 |||....:|::|..||             :...:.|...:|
  Fly     5 KATTRAAITSGHHQLQQAVNPILGALGAATRKGLTRRAAATGNIDPNVENMQTRAKRKADHSPIK 69

  Fly    67 LTDALRNAKARVDSHWKKQPLGSTNGNGNGAVPPKVNEGGVSAFLRSNSVRNRVPTKTTVEPTKV 131
            .....|:|...:.::.|...|..........|..|.....:.|.:.:....|.  :......:|:
  Fly    70 NDKIKRSALGNLTNNVKIMTLHPAQDEEQSGVGKKPTAQQLQALMDAKKQENL--SVNVFGASKM 132

  Fly   132 TVKSSSSENVNEPTLKREDS-NLSKKSLTKLRAALAKPVMGVSGIRREPVAVSRKEAETKKELPE 195
            |.::||         |.||| ....|.|.||..|||:|..     |.:.|..::|....:.:||.
  Fly   133 TTRASS---------KVEDSVENCHKVLDKLEEALARPKP-----RPKAVPAAKKTVLGEVQLPA 183

  Fly   196 TKK-----------DSLEVKKDATRMPLIRGNSAVTTT-----TSTMPTTMSLSSKRLAG----- 239
            ...           .:|...:.|...|:.|.::....|     .|.:....|..|.||:|
  Fly   184 MPNPMQIPVLLPPTHNLAAPQVAAVKPVRRISNDFNKTEDSLYMSALEDVSSCDSMRLSGNFEAA 248

  Fly   240 ---------------------------------------IEDIDANDKENLVLVSEYVNDIYDYL 265
                                                   :||.|..:.::...||.|..||::||
  Fly   249 RRRSAKLQQKTEQQPQPLLLTLPETAPSQVVPIPPVPEEVEDFDRKNWDDPFQVSHYAMDIFNYL 313

  Fly   266 YQVELEQPIHKDHLAGQKEVSHKMRAVLIDWINEVHLQFHLAAETFQLAVAIIDRYL--QVVKDT 328
            ...|.|.|| .|::..|..::..||.:|:||:.||...|.|..||..|||.|:|.||  :|:...
  Fly   314 KVREAEFPI-ADYMPRQIHLTTWMRTLLVDWMVEVQETFELNHETLYLAVKIVDLYLCREVINKE 377

  Fly   329 KRTYLQLVGVTALFIATKYEELFPPAIGDFVFITDDTYTARQIRQMELQIFKAIDCNLSRPLPIH 393
            |   |||:|..|.|||.||:|..||.|.||::|.|..|...::.:||.:..:.|..:|..||...
  Fly   378 K---LQLLGAAAFFIACKYDERQPPLIEDFLYICDGAYNHDELVRMERETLRVIKYDLGIPLSYR 439

  Fly   394 FLRRYSKAAGAEDEHHTMSKYFIELASVDYEMATYRPSEIAAASLFLSLHLLNGNHRAGTGFNDR 458
            |||||::.|.......|:::|.:||:.:||...::..|::|:|:||::|.:     ..|.|..|:
  Fly   440 FLRRYARCAKVPMPTLTLARYILELSLMDYANISFSDSQMASAALFMALRM-----HGGPGQLDK 499

  Fly   459 H-WTPTLTFYSRYSAAHLRPI-TRLIAKLARDAPQAKLKAIYNKYQGSKFQKIA 510
            . ||.||.:|:.|..|....| |.|.|.|.| .|:|.:|.|.|||....|.::|
  Fly   500 QTWTSTLIYYTGYQLADFAEIVTALNAGLHR-KPRATIKTIRNKYSHKIFHEVA 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycB	NP_726244.1	CYCLIN_CCNB1-like_rpt1	254..384	CDD:410211	55/131 (42%)
		CYCLIN_CCNB1-like_rpt2	389..509	CDD:410213	44/121 (36%)
CycB3	NP_651303.2	CYCLIN_CCNB3_rpt1	290..431	CDD:410212	57/144 (40%)
		CYCLIN_CCNB3_rpt2	435..555	CDD:410214	45/124 (36%)