DRSC/TRiP Functional Genomics Resources

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Protein Alignment CycB and ccne1

DIOPT Version :10

Sequence 1:NP_726244.1 Gene:CycB / 37618 FlyBaseID:FBgn0000405 Length:530 Species:Drosophila melanogaster
Sequence 2:NP_571070.1 Gene:ccne1 / 30188 ZFINID:ZDB-GENE-980526-168 Length:410 Species:Danio rerio


Alignment Length:359 Identity:92/359 - (25%)
Similarity:148/359 - (41%) Gaps:90/359 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   118 NRVPTKTTVEPTK----VTVK-SSSSENVNEPTLKREDSNLSKKSLTKLRAALAKPVMG-VSGIR 176
            :..|..|:|.|.|    |.:. ....|.|.|.|.|::.::          .|...|..| .|..|
Zfish    16 DEAPKTTSVRPRKRKADVAIHLQDPDEEVTEMTRKKQCAS----------QACWNPDTGYTSPCR 70

  Fly   177 REPVAVSRKEAETKKELPETKKDSLEVKKDATRMPLIRGNSA----------VTTTTSTMPTTMS 231
            |.|         |..|:.|               |:..|:..          :|.|.||....:.
Zfish    71 RIP---------TPDEVEE---------------PVAFGSVGFTQYASESIFITPTRSTPLPALC 111

  Fly   232 LSSKRLAGIEDIDAN--DKENLVLVSEYVNDIYDYLYQVELEQPIHKDHLAGQKEVSHKMRAVLI 294
            .:||     :::..|  .|:.|.|....|.:.:..|      ||              ||||:|:
Zfish   112 WASK-----DEVWNNLLGKDKLYLRDTRVMERHPNL------QP--------------KMRAILL 151

  Fly   295 DWINEVHLQFHLAAETFQLAVAIIDRYLQVVKDTKRTYLQLVGVTALFIATKYEELFPPAIGDFV 359
            ||:.||...:.|..|||.|.....||::...::..:|.|||:|::.||||.|.||::||.:..|.
Zfish   152 DWLMEVCEVYKLHRETFYLGQDYFDRFMATQENVLKTTLQLIGISCLFIAAKMEEIYPPKVHQFA 216

  Fly   360 FITDDTYTARQIRQMELQIFKAIDCNLSRPLPIHFLRRYSKAAGAEDEHHTMSKYF--------- 415
            ::||...|...|..||:.|.|.::.:||...|:.:|..|.:.|..::....::..:         
Zfish   217 YVTDGACTEDDILSMEIIIMKELNWSLSPLTPVAWLNIYMQMAYLKETAEVLTAQYPQATFVQIA 281

  Fly   416 --IELASVDYEMATYRPSEIAAASL--FLSLHLL 445
              ::|..:|.....:..|.:||::|  |.||.|:
Zfish   282 ELLDLCILDVRSLEFSYSLLAASALFHFSSLELV 315

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CycBNP_726244.1 CYCLIN_CCNB1-like_rpt1 254..384 CDD:410211 43/129 (33%)
CYCLIN_CCNB1-like_rpt2 389..509 CDD:410213 14/70 (20%)
ccne1NP_571070.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..31 5/14 (36%)
CYCLIN_CCNE1_rpt1 105..241 CDD:410282 50/160 (31%)
CYCLIN_SF 245..358 CDD:477360 14/71 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 387..410
Blue background indicates that the domain is not in the aligned region.

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