Protein Alignment CycB and cdc13

DIOPT Version :10

• Sequence 1: NP_726244.1
• Gene: CycB / 37618
• FlyBaseID: FBgn0000405
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001342891.1
• Gene: cdc13 / 2540880
• PomBaseID: SPBC582.03
• Length: 482
• Species: Schizosaccharomyces pombe
• Alignment Length: 509
• Identity: 145/509 - (28%)
• Similarity: 230/509 - (45%)
• Gaps: 110/509 - (21%)

  Fly    13 NASENFKQVQLKKLTVPSMEATTKRAALGDLQN----RGISRPIAAKDAAQKDSKDLKLTDALRN 73
            ::||| ..|..||.||.|.....||.||.|:.|    .|:  |:|:|:.            .:|:
pombe    36 HSSEN-SLVNGKKATVSSTNVPKKRHALDDVSNFHNKEGV--PLASKNT------------NVRH 85

  Fly    74 AKARVDSHWKKQPLGSTNGNGNGAVPPKVNEGGVSAFLRSNSVRNRVPTKTTVEPTKVTVKSSSS 138
            ..|.|.:.                              |:...::.:|. |..||.....:..|.
pombe    86 TTASVSTR------------------------------RALEEKSIIPA-TDDEPASKKRRQPSV 119

  Fly   139 ENVNEPTLKREDSNLSKKSLTKLRAALAKPVMGVSGIRREPVAVSRK------EAETKKELPETK 197
            .|.:.|:|.:..|..|....|.          ||....::...:.:|      |....|::|:..
pombe   120 FNSSVPSLPQHLSTKSHSVSTH----------GVDAFHKDQATIPKKLKKDVDERVVSKDIPKLH 174

  Fly   198 KDSLEVKKDATRMPLIRGNSAVTTTTSTMPTTMSLSSKRLAGIEDIDANDKENLVLVSEYVNDIY 262
            :||:|                               |......:|:||.|..:.::|||||.||:
pombe   175 RDSVE-------------------------------SPESQDWDDLDAEDWADPLMVSEYVVDIF 208

  Fly   263 DYLYQVELEQPIHKDHLAGQKEVSHKMRAVLIDWINEVHLQFHLAAETFQLAVAIIDRYLQVVKD 327
            :||.::|:|......::..|||::.|||.:|.||:.|||.:|.|..||..|||.||||:|. ::.
pombe   209 EYLNELEIETMPSPTYMDRQKELAWKMRGILTDWLIEVHSRFRLLPETLFLAVNIIDRFLS-LRV 272

  Fly   328 TKRTYLQLVGVTALFIATKYEELFPPAIGDFVFITDDTYTARQIRQMELQIFKAIDCNLSRPLPI 392
            .....|||||:.|||||:||||:..|::.:||::.|..|...:|.|.|..|.:.::.||:.|.|:
pombe   273 CSLNKLQLVGIAALFIASKYEEVMCPSVQNFVYMADGGYDEEEILQAERYILRVLEFNLAYPNPM 337

  Fly   393 HFLRRYSKAAGAEDEHHTMSKYFIELASVDYEMATYRPSEIAAASLFLSLHLLNGNHRAGTGFND 457
            :||||.|||...:.:..|::||.:|:..:|:::..|.||:..||:::|:..:|      |.|
pombe   338 NFLRRISKADFYDIQTRTVAKYLVEIGLLDHKLLPYPPSQQCAAAMYLAREML------GRG--- 393

  Fly   458 RHWTPTLTFYSRYSAAHLRPITRLIAKLARDAPQAKLKAIYNKYQGSKFQKIAL 511
             .|...|..||.|....|..:.:.:....:...|.  :|.:.||...||.|.:|
pombe   394 -PWNRNLVHYSGYEEYQLISVVKKMINYLQKPVQH--EAFFKKYASKKFMKASL 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycB	NP_726244.1	CYCLIN_CCNB1-like_rpt1	254..384	CDD:410211	58/129 (45%)
		CYCLIN_CCNB1-like_rpt2	389..509	CDD:410213	35/119 (29%)
cdc13	NP_001342891.1	COG5024	5..454	CDD:227357	145/509 (28%)