Protein Alignment CycB and cya-1

DIOPT Version :10

• Sequence 1: NP_726244.1
• Gene: CycB / 37618
• FlyBaseID: FBgn0000405
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_499018.1
• Gene: cya-1 / 176287
• WormBaseID: WBGene00000863
• Length: 485
• Species: Caenorhabditis elegans
• Alignment Length: 471
• Identity: 122/471 - (25%)
• Similarity: 198/471 - (42%)
• Gaps: 78/471 - (16%)

  Fly    93 NGNGAVPPKVNEGGV--SAFL---------RSNSVRNRVPTKTTVEPTKVTV------------- 133
            |||.|....||...|  :|.|         .||.::..:|:|...|...:.:
 Worm    11 NGNAAKSQAVNNKNVIKNAPLGGKLTRQIGTSNLLQQALPSKKIDESPIIKIDAKDSFKVFEDQE 75

  Fly   134 --KSSSSENV-----NEPTLKREDSN----LSKKSLTKLRAALAK-PVMGVSGIRREPVAVSRKE 186
              |.:|||||     :...:..||:|    |.:|...|.||...| ..|..    |:...::.:.
 Worm    76 PEKENSSENVDATEKDSNVIPAEDNNMIHELERKMEEKSRAEKLKFKFMQT----RDNSDITSRF 136

  Fly   187 AETKKELPETKKDSLEVKKDATRMPLIRGNSAVTTTTSTMPTTMSL-----SSKRLAGIEDI--- 243
            :|...|......|.     |..::.:    ::.|.|||...|..|.     ..|:..|.|:.
 Worm   137 SEPPSEFSVLCDDD-----DCDKVSV----ASSTFTTSVRATFSSFHFDENQRKKEFGKEEAVKK 192

  Fly   244 -------DANDKENLVLVSEYVNDIYDYLYQVELEQPIHKDHLAGQKEVSHKMRAVLIDWINEVH 301
                   :|.| :::....|:..||..|:...:.:.....:....|.:|:.:||.:||||.::|.
 Worm   193 IQKKAAKEARD-DSMFSSEEFFPDIIKYMLHRQTKNRASHECFDIQSQVNEEMRTILIDWFSDVV 256

  Fly   302 LQFHLAAETFQLAVAIIDRYLQVVKDTKRTYLQLVGVTALFIATKYEELFPPAIGDFVFITDDTY 366
            .:::...|||.|||:::||.|.:....|..: ||||.|::.||.||||:|||.|.||..|||:||
 Worm   257 KEYNFQKETFHLAVSLVDRALSMFNIDKMRF-QLVGTTSMMIAVKYEEIFPPEIEDFALITDNTY 320

  Fly   367 TARQIRQMELQIFKAIDCNLSRPLPIHFLRRYSKAAGAEDEHHTMSKYFIELASVDYEMATYRPS 431
            ....|..||..:....|..::.|....|...::|......:......|.:||:.:|.....||||
 Worm   321 RVPDILLMERFLLGKFDFVVAMPTSSWFGTCFAKRMNFTKKMRNTVHYLLELSLIDVHFLRYRPS 385

  Fly   432 EIAAAS-LFLSLHLLNGNHRAGTGFNDRHWTPTLTFYSRYSAAHLRPITRLIAKLARDAPQAKLK 495
            :||||: .|.:|..           :...|...:...:..|......:.|.:.::..:|..|..|
 Worm   386 DIAAAACCFANLQA-----------DVESWPQKMVDDTGISTEDFVDVLRDLHRMYLNASTADFK 439

  Fly   496 AIYNKYQGSKFQKIAL 511
            :|:..|..:...::||
 Worm   440 SIFYNYSETAQMEVAL 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycB	NP_726244.1	CYCLIN_CCNB1-like_rpt1	254..384	CDD:410211	48/129 (37%)
		CYCLIN_CCNB1-like_rpt2	389..509	CDD:410213	25/120 (21%)
cya-1	NP_499018.1	Cyclin_N	215..338	CDD:459686	47/123 (38%)
		CYCLIN_CCNA_rpt2	343..451	CDD:410209	25/118 (21%)