DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42260 and CNGC18

DIOPT Version :9

Sequence 1:	NP_001356969.1	Gene:	CG42260 / 37614	FlyBaseID:	FBgn0259145	Length:	1269	Species:	Drosophila melanogaster
Sequence 2:	NP_196991.1	Gene:	CNGC18 / 831339	AraportID:	AT5G14870	Length:	706	Species:	Arabidopsis thaliana

Alignment Length:	560	Identity:	133/560 - (23%)
Similarity:	221/560 - (39%)	Gaps:	132/560 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   570 HFVFDPAGRLCYYWSMV-----VSMAFL--YNFWV----------IIYRFAFQEINRRTIAIWFC 617
            |.:.||...:..||:.|     :...||  :.|:|          |....|......||:|
plant    38 HQILDPDSNIVTYWNHVFLITSILALFLDPFYFYVPYVGGPACLSIDISLAATVTFFRTVA---- 98

  Fly   618 LDYLSDFLYLIDILFHFRTGYLE-------DGVLQTDALKLRTHYMNSTIFYIDCLCLLPLDFLY 675
                 |..:|:.|...|||.::.       .|.|..|:.::...|: .|.|.||...:|||..|.
plant    99 -----DIFHLLHIFMKFRTAFVARSSRVFGRGELVMDSREIAMRYL-KTDFLIDVAAMLPLPQLV 157

  Fly   676 LSIGF-----------NSIL----------RSFRLV----KIYRFWAFMDRTERHTNYPNLFRST 715
            :.:..           ||.|          |||.:.    :|.:...|:.:|.......||....
plant   158 IWLVIPAATNGTANHANSTLALIVLVQYIPRSFIIFPLNQRIIKTTGFIAKTAWAGAAYNLLLYI 222

  Fly   716 ALIH------YLLVIFHWNGCLYHIIHKNNGF------------------GSRNW------VYH- 749
            ...|      ||..|.....|..::..|:|..                  ..:.|      :.|
plant   223 LASHVLGAMWYLSSIGRQFSCWSNVCKKDNALRVLDCLPSFLDCKSLEQPERQYWQNVTQVLSHC 287

  Fly   750 DSESA--------------------DVVKQYLQSYYWCTLALTTIG-DLPKPRSKGEYVFVILQL 793
            |:.|:                    |.|.:||...:|....|::.| ::......||.:|.|...
plant   288 DATSSTTNFKFGMFAEAFTTQVATTDFVSKYLYCLWWGLRNLSSYGQNITTSVYLGETLFCITIC 352

  Fly   794 LFGLMLFATVLGHVANIVTSVSAARKEFQAKLDGVKTYMRMRRVPNHLQVKVIKWFDYLWLTQKC 858
            :|||:||..::|::.:.:.|:|...:|::.|....:.:||.|::|..||.:|.::..|.||..:.
plant   353 IFGLILFTLLIGNMQSSLQSMSVRVEEWRVKRRDTEEWMRHRQLPPELQERVRRFVQYKWLATRG 417

  Fly   859 SDEERAVSCLPDKLKAEIAINVHLDTLKRVEIFQNTEAGFLCELVLRLRPVLFSPGDYICRKGEV 923
            .|||..:..||..|:.||..::.|..::||..|...:...|..:...|...|.:.|.||.|:|:.
plant   418 VDEESILHSLPTDLRREIQRHLCLSLVRRVPFFSQMDDQLLDAICGCLVSSLSTAGTYIFREGDP 482

  Fly   924 GKEMYIVNRGRLQVVADNGKTV----MASLKAGSYFGE---------ISILNMGTAGNRRTASVR 975
            ..||..|.||:::....||...    ..:|:.|.:.||         .|.||:.::    |.|||
plant   483 VNEMLFVIRGQIESSTTNGGRSGFFNSTTLRPGDFCGEELLTWALMPNSTLNLPSS----TRSVR 543

  Fly   976 SVGYSDLFVLSKKDMWDVLKEYPAARVRLESIAVKRLEKY 1015
            ::...:.|.||.:|:..|..::.    ||:|..::...:|
plant   544 ALSEVEAFALSAEDLKFVAHQFK----RLQSKKLQHAFRY 579

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42260	NP_001356969.1	Ion_trans	581..819	CDD:334124	71/338 (21%)
		CAP_ED	890..1004	CDD:237999	32/126 (25%)
		DUF4655	1084..>1154	CDD:317882
CNGC18	NP_196991.1	Ion_trans	92..378	CDD:278921	62/295 (21%)
		Crp	443..>579	CDD:223736	37/143 (26%)
		CAP_ED	449..580	CDD:237999	36/139 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	53	1.000	Domainoid score	I4197
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1073751at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920