Protein Alignment CG42260 and Cnga2

DIOPT Version :10

• Sequence 1: NP_001356969.1
• Gene: CG42260 / 37614
• FlyBaseID: FBgn0259145
• Length: 1269
• Species: Drosophila melanogaster
• Sequence 2: XP_006527824.1
• Gene: Cnga2 / 12789
• MGIID: 108040
• Length: 664
• Species: Mus musculus
• Alignment Length: 483
• Identity: 229/483 - (47%)
• Similarity: 311/483 - (64%)
• Gaps: 26/483 - (5%)

  Fly   529 HGGAGSGGGSGPGSHGGQPHHQKPRRTASQRIRAATAARKLHFVFDPAGRLCYYWSMVVSMAFLY 593
            |.|.|.|...|.|.                    .|..:...||.||||...|.|..|::|..||
Mouse   111 HQGDGKGDKDGEGK--------------------GTKKKFELFVLDPAGDWYYRWLFVIAMPVLY 155

  Fly   594 NFWVIIYRFAFQEINRRTIAIWFCLDYLSDFLYLIDILFHFRTGYLEDGVLQTDALKLRTHYMNS 658
            |:.:::.|..|.::.|....:|..|||.||.:|:.|::...|||:||.|:|..|..|||.:|:::
Mouse   156 NWCLLVARACFSDLQRNYFVVWLVLDYFSDTVYIADLIIRLRTGFLEQGLLVKDPKKLRDNYIHT 220

  Fly   659 TIFYIDCLCLLPLDFLYLSIGFNS-ILRSFRLVKIYRFWAFMDRTERHTNYPNLFRSTALIHYLL 722
            ..|.:|...::|.|.:|.::|.:| .:|..||:...|.:.|.||||..|:|||:||.:.|:.|:|
Mouse   221 LQFKLDVASIIPTDLIYFAVGIHSPEVRFNRLLHFARMFEFFDRTETRTSYPNIFRISNLVLYIL 285

  Fly   723 VIFHWNGCLYHIIHKNNGFGSRNWVY---HDSESADVVKQYLQSYYWCTLALTTIGDLPKPRSKG 784
            ||.|||.|:|:.|.|:.|||...|||   .|.|...:.::|:...||.||.|||||:.|.|....
Mouse   286 VIIHWNACIYYAISKSIGFGVDTWVYPNITDPEYGYLAREYIYCLYWSTLTLTTIGETPPPVKDE 350

  Fly   785 EYVFVILQLLFGLMLFATVLGHVANIVTSVSAARKEFQAKLDGVKTYMRMRRVPNHLQVKVIKWF 849
            ||:|||...|.|:::|||::|:|.:::::::|.|.|||||:|.||.||:.|:|...::.||||||
Mouse   351 EYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKDMEAKVIKWF 415

  Fly   850 DYLWLTQKCSDEERAVSCLPDKLKAEIAINVHLDTLKRVEIFQNTEAGFLCELVLRLRPVLFSPG 914
            ||||..:|..||...:..||.||:|||||||||.|||:|.|||:.|||.|.||||:|||.:||||
Mouse   416 DYLWTNKKTVDEREVLKNLPAKLRAEIAINVHLSTLKKVRIFQDCEAGLLVELVLKLRPQVFSPG 480

  Fly   915 DYICRKGEVGKEMYIVNRGRLQVVADNGKTVMASLKAGSYFGEISILNM--GTAGNRRTASVRSV 977
            |||||||::||||||:..|:|.||||:|.|..|.|.|||.||||||||:  ...||||||::||:
Mouse   481 DYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSL 545

  Fly   978 GYSDLFVLSKKDMWDVLKEYPAARVRLE 1005
            ||||||.|||.|:.:.:.|||.|:..||
Mouse   546 GYSDLFCLSKDDLMEAVTEYPDAKKVLE 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42260	NP_001356969.1	Ion_trans	581..820	CDD:459842	98/242 (40%)
		CAP_ED	890..1004	CDD:237999	74/115 (64%)
Cnga2	XP_006527824.1	Ion_trans	142..384	CDD:459842	97/241 (40%)
		CAP_ED	456..572	CDD:237999	74/115 (64%)
		CLZ	572..639	CDD:465160	2/2 (100%)