DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ppa and RPP1

DIOPT Version :9

Sequence 1:	NP_001261138.1	Gene:	Ppa / 37602	FlyBaseID:	FBgn0020257	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_001326420.1	Gene:	RPP1 / 823573	AraportID:	AT3G44480	Length:	1240	Species:	Arabidopsis thaliana

Alignment Length:	447	Identity:	111/447 - (24%)
Similarity:	185/447 - (41%)	Gaps:	103/447 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 GTHIS--------NLFPELLEQI--FEHLPVRDLGRAAQVCTAWRDAAY----AKSV-WKGVEAK 195
            |.|:.        |:..::||::  |..:.:....:..::..|.:|..|    .:|: |.|.|:
plant   618 GIHLELSNTEEELNISEKVLERVHDFHFVRIDASFQPERLQLALQDLIYHSPKIRSLNWYGYES- 681

  Fly   196 LHLKRSSPSLFN--CLVKRGIKKVQILSLRRS-LKDLVLGVPALTSL---------------NLS 242
            |.|    ||.||  .||:        |.:|.| |:.|..|...|.:|               |||
plant   682 LCL----PSTFNPEFLVE--------LDMRSSNLRKLWEGTKQLRNLKWMDLSYSSYLKELPNLS 734

  Fly   243 GCFNVADMNLGHAFS-VDLP-------NLKTLDLSLCKQITDTSLGRI--AQHLRNLETLELGGC 297
            ...|:.::.|.:..| |:||       :|:.|||..|     :||.::  .::...|..|:|..|
plant   735 TATNLEELKLRNCSSLVELPSSIEKLTSLQILDLENC-----SSLEKLPAIENATKLRELKLQNC 794

  Fly   298 CNITNTGLLLIAWGLKKLKHLNLRSC----------WHISDQGIGHLAGFSR----ETAEGNLQ- 347
            .::..  |.|.......||.||:..|          ..|:|..:..|:..|.    .::.||||
plant   795 SSLIE--LPLSIGTATNLKQLNISGCSSLVKLPSSIGDITDLEVFDLSNCSSLVTLPSSIGNLQN 857

  Fly   348 LEYLGLQDCQRLSDEALGHIAQGLTSLKSINLSFC--------VSVTDSGLKHLARMPKLEQLNL 404
            |..|.::.|.:|  ||| .|...|.||.::||:.|        :|...|.|:......|...|::
plant   858 LCKLIMRGCSKL--EAL-PININLKSLDTLNLTDCSQLKSFPEISTHISELRLKGTAIKEVPLSI 919

  Fly   405 RSCDNISDIGMAYLTEGGSGINSLDVSFCDKISD--QALTHIAQGLYRLRSLSLNQCQITDHGML 467
            .|...::|..::|........::.|:.....:|.  |.:....:.:.|||.||||.|    :.::
plant   920 MSWSPLADFQISYFESLMEFPHAFDIITKLHLSKDIQEVPPWVKRMSRLRDLSLNNC----NNLV 980

  Fly   468 KIAKALHELENLNIGQCSRITDKGLQTLAEDLTNLKTIDLY--GCTQLSSKGIDIIM 522
            .:.:....|:.:....|     |.|:.| :...|...|.||  .|.:|:.:..|:||
plant   981 SLPQLSDSLDYIYADNC-----KSLERL-DCCFNNPEIRLYFPKCFKLNQEARDLIM 1031

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689	8/55 (15%)
		AMN1	<226..>334	CDD:187754	34/142 (24%)
		leucine-rich repeat	236..256	CDD:275381	7/34 (21%)
		leucine-rich repeat	263..288	CDD:275381	7/26 (27%)
		leucine-rich repeat	289..314	CDD:275381	6/24 (25%)
		leucine-rich repeat	315..347	CDD:275381	11/45 (24%)
		AMN1	347..524	CDD:187754	48/189 (25%)
		leucine-rich repeat	348..373	CDD:275381	9/24 (38%)
		leucine-rich repeat	374..398	CDD:275381	7/31 (23%)
		leucine-rich repeat	399..424	CDD:275381	4/24 (17%)
		leucine-rich repeat	425..450	CDD:275381	3/26 (12%)
		leucine-rich repeat	451..475	CDD:275381	7/23 (30%)
		leucine-rich repeat	476..501	CDD:275381	5/24 (21%)
RPP1	NP_001326420.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010