Protein Alignment RYBP and RYBP

DIOPT Version :10

• Sequence 1: NP_611705.1
• Gene: RYBP / 37601
• FlyBaseID: FBgn0034763
• Length: 150
• Species: Drosophila melanogaster
• Sequence 2: NP_036366.3
• Gene: RYBP / 23429
• HGNCID: 10480
• Length: 228
• Species: Homo sapiens
• Alignment Length: 209
• Identity: 86/209 - (41%)
• Similarity: 103/209 - (49%)
• Gaps: 60/209 - (28%)

  Fly     1 MDKKSSPVRRQKRQAK-VIEENFWDCSVCTYRNSAEAFKCRMCDVRKGTSTRKPRLNSALVAQQA 64
            |..|.||. |.||||| ..:|.||||||||:|||||||||.:|||||||||||||:||.|||||.
Human     3 MGDKKSPT-RPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQV 66

  Fly    65 A-------------------------------------------TLPGASV--NMPNGKSASGSR 84
            |                                           |.|.:.:  :.|:..::..|.
Human    67 AQQYATPPPPKKEKKEKVEKQDKEKPEKDKEISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSA 131

  Fly    85 HGSGHDRQRHKRYPARLKNVDRSTAQTREVTVNSVTVFITEYKAKPVSSRRES--------SEQ- 140
            :.:....:.:.....|||||||||||...|||.:|||.||::|.|..||...|        |||
Human   132 NATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQ 196

  Fly   141 ----SFSESNDSRS 150
                |.|||.|..|
Human   197 NQSSSGSESTDKGS 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RYBP	NP_611705.1	zf-RanBP	20..43	CDD:395516	18/22 (82%)
		RanBP2-type Zn finger	23..42	CDD:275377	16/18 (89%)
		YAF2_RYBP	98..130	CDD:465386	20/31 (65%)
RYBP	NP_036366.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		10/18 (56%)
		zf-RanBP	22..45	CDD:395516	18/22 (82%)
		RanBP2-type Zn finger	25..44	CDD:275376	16/18 (89%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..156		39/146 (27%)
		Interaction with GABPB1 and FANK1. /evidence=ECO:0000269|PubMed:11953439, ECO:0000269|PubMed:27060496	143..226		6/10 (60%)
		YAF2_RYBP	145..176	CDD:465386	5/8 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	172..228