DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cdk9 and CDK11A

DIOPT Version :8

Sequence 1:NP_477226.2 Gene:Cdk9 / 37586 FlyBaseID:FBgn0019949 Length:404 Species:Drosophila melanogaster
Sequence 2:NP_001300825.1 Gene:CDK11A / 728642 HGNCID:1730 Length:783 Species:Homo sapiens

Alignment Length:440 Identity:148/441 (34%)
Similarity:220/441 (50%) Gaps:76/441 (17%)


  Fly     5 SHMLQQP----------SGSTPSNVGSSSSRTMSLMEKQKYIED----------YDFPY------ 43
            :|:|..|          |......||..:.::.:|.|.. |:.|          .:.|.      
Human   355 NHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGD-YVPDSPALLPIELKQELPKYLPALQ 418

  Fly    44 -CDESNKYEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEKEGFPITALREIRILQLLKH 107
             |....:::.:.:|.:||:|.|::|::|| ..:.||:|::.|:.||||||||:||||..:...:|
Human   419 GCRSVEEFQCLNRIEEGTYGVVYRAKDKK-TDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 482

  Fly   108 ENVVNLIEICRTKATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGEIKKVMQQLLNGLYYI 172
            .|:|.:.||      .........|:|.::.||||..|:..|...|..||:|.:|.|||.|:.::
Human   483 PNIVTVREI------VVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 541

  Fly   173 HSNKILHRDMKAANVLITKHGILKLADFGLARAFSIPKNESKNRYTNRVVTLWYRPPELLLGDRN 237
            |.|.|||||:|.:|:|::..||||:.||||||.:..|    ...||..|||.|||.||||||.:.
Human   542 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP----LKAYTPVVVTQWYRAPELLLGAKE 602

  Fly   238 YGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPDVWPGVEELELYKSIELPKN 302
            |...||||..|||..|:.|:.|:..||:|..|:..:.:..|:.:..:|||..||.:.|.:...::
Human   603 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEH 667

  Fly   303 QKRRVKERLRPYVKDQTGCDLLDKLLTLDPKKRIDADTALNHDFFWTDPMPSDLSKMLSQHLQSM 367
            ....:::|....:.|| |.||::|.||..|.:||.|:..|.|::|...|:|.|         .||
Human   668 PYNNLRKRFGALLSDQ-GFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID---------PSM 722

  Fly   368 FEYLAQPRRSNQMR--------------NYHQ-----------QLTTMNQ 392
            |.  ..|.:|.|.|              .|.|           .|||.||
Human   723 FP--TWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQ 770

Known Domains:


GeneSequenceDomainRegion External IDIdentity
Cdk9NP_477226.2 STKc_CDK9 37..347 CDD:270848 121/327 (37%)
S_TKc 50..347 CDD:214567 118/297 (40%)
CDK11ANP_001300825.1 STKc_CDC2L1 420..711 CDD:173741 119/303 (39%)
PLN00009 423..713 CDD:177649 119/302 (39%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 D925637at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.010

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