Protein Alignment Cdk9 and Cdk12

DIOPT Version :8

• Sequence 1: NP_477226.2
• Gene: Cdk9 / 37586
• FlyBaseID: FBgn0019949
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_001103096.1
• Gene: Cdk12 / 69131
• MGIID: 1098802
• Length: 1484
• Species: Mus musculus
• Alignment Length: 334
• Identity: 153/335 (46%)
• Similarity: 213/335 (64%)
• Gaps: 15/335 (4%)

  Fly    48 NKYEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEKEGFPITALREIRILQLLKHENVVN 112
            :|::.:..||:||:|:|:||:: |...:.||:|||.:|||||||||||:|||:||:.|.|::|||
Mouse   721 DKFDIIGIIGEGTYGQVYKAKD-KDTGELVALKKVRLDNEKEGFPITAIREIKILRQLVHQSVVN 784

  Fly   113 LIEICRTKATATN--GYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGEIKKVMQQLLNGLYYIHSN 175
            :.||...|..|.:  ..:..|||||::.:|||.|||.:..|.||...||..|:||:.||.|.|..
Mouse   785 MKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLDYCHKK 849

  Fly   176 KILHRDMKAANVLITKHGILKLADFGLARAFSIPKNESKNRYTNRVVTLWYRPPELLLGDRNYGP 240
            ..||||:|.:|:|:...|.:|||||||||.::   :|....|||:|:||||||||||||:..|.|
Mouse   850 NFLHRDIKCSNILLNNSGQIKLADFGLARLYN---SEESRPYTNKVITLWYRPPELLLGEERYTP 911

  Fly   241 PVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPDVWPGVEELELYKSIELPKNQKR 305
            .:|:|..|||:.|::|:.||.|.|.|..||..||:||||..|.|||.|.:|..:.:::..|..:|
Mouse   912 AIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRR 976

  Fly   306 RVKERLRPYVKDQTGCDLLDKLLTLDPKKRIDADTALNHDFFWTDPMPSDLSKMLS---QHLQSM 367
            |::|.. .:: .....||||.:|||||.||..|:..|..||.    ...:||||..   .|.|..
Mouse   977 RLREEF-SFI-PSAALDLLDHMLTLDPSKRCTAEQTLQSDFL----KDVELSKMAPPDLPHWQDC 1035

  Fly   368 FEYLAQPRR 376
            .|..::.||
Mouse  1036 HELWSKKRR 1044

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk9	NP_477226.2	STKc_CDK9	37..347	CDD:270848	144/301 (48%)
		S_TKc	50..347	CDD:214567	143/299 (48%)
Cdk12	NP_001103096.1	STKc_CDK12	715..1016	CDD:270847	144/301 (48%)
		S_TKc	723..1016	CDD:214567	143/299 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D925637at2759
OrthoFinder	1	1.000				FOG0000559
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R186
TreeFam	0	0.000	Not matched by this tool.
	3	3.040