Protein Alignment Cdk9 and Cdk4

DIOPT Version :10

• Sequence 1: NP_477226.2
• Gene: Cdk9 / 37586
• FlyBaseID: FBgn0019949
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Alignment Length: 331
• Identity: 117/331 - (35%)
• Similarity: 185/331 - (55%)
• Gaps: 28/331 - (8%)

  Fly    30 MEKQKYIEDYDFPYCDESNKYEKVAKIGQGTFGEVFKAREK-KGNKKFVAMKKVLMDNEKEGFPI 93
            :::||..:...|...|..| |:::..||:|.:|.|::||:. .||  .||:|||.:...:.|.|:
  Fly     7 LKRQKMSQAKKFGDGDPFN-YQELNIIGEGAYGTVYRARDVITGN--IVALKKVRISLNENGVPM 68

  Fly    94 TALREIRILQLL---KHENVVNLIEICRTKATATNGYRSTFYLVFDFCEHDLAGLLSNM-NVKFS 154
            :.||||.:|:.|   .|.|:|.|.|:|  :....:| :....|||:..|.||:.|:..: ....|
  Fly    69 STLREISLLKQLNASNHANIVKLYEVC--QFLERDG-QLLILLVFEHVEQDLSDLIDRLPKSGMS 130

  Fly   155 LGEIKKVMQQLLNGLYYIHSNKILHRDMKAANVLITKHGILKLADFGLARAFSIPKNESKNRYTN 219
            ...|:::.::||.|:.::||::|:|||:|..|:|::..|.||:||||||:.:.     |:.:.|:
  Fly   131 PPTIQRLSRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAKTYG-----SEMKLTS 190

  Fly   220 RVVTLWYRPPELLLGDRNYGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPDV 284
            .|||||||.||:||. :.|...||:|.|.||:.||:.|..:..|.:|:.||..|.:|.|..|...
  Fly   191 VVVTLWYRAPEVLLA-QPYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQ 254

  Fly   285 WPGVEELELYKSIELPKNQKRRVKE---RLRPYVKDQTGCDLLDKLLTLDPKKRIDADTALNHDF 346
            ||....:.|.   ..|:...:|.|:   .|..|..     |||:|:|:.|...|..|...|.||:
  Fly   255 WPQTISVALE---HFPQRHPKRPKDFCPHLCKYAD-----DLLNKMLSYDLHLRPSALACLEHDY 311

  Fly   347 FWTDPM 352
            |..:|:
  Fly   312 FQQEPL 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk9	NP_477226.2	STKc_CDK9	37..347	CDD:270848	113/317 (36%)
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	110/304 (36%)