Protein Alignment Cdk9 and CDK20

DIOPT Version :10

• Sequence 1: NP_477226.2
• Gene: Cdk9 / 37586
• FlyBaseID: FBgn0019949
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: XP_047279074.1
• Gene: CDK20 / 23552
• HGNCID: 21420
• Length: 364
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 123/330 - (37%)
• Similarity: 180/330 - (54%)
• Gaps: 31/330 - (9%)

  Fly    48 NKYEKVAKIGQGTFGEVFKAREKK------------GNKKFVAMKKVLMDNEKEGFPITALREIR 100
            ::|..:.:||:|..|.||||:..:            ...:.||:|||.:...::|||..|||||:
Human     2 DQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQALREIK 66

  Fly   101 ILQLLK-HENVVNLIEICRTKATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGEIKKVMQQ 164
            .||.:: ::.||.|      ||...:|  ..|.|.|:|...|||.::.:.....:..::|..:|.
Human    67 ALQEMEDNQYVVQL------KAVFPHG--GGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQM 123

  Fly   165 LLNGLYYIHSNKILHRDMKAANVLITKHGILKLADFGLARAFSIPKNESKNRYTNRVVT-----L 224
            ||.|:.:.|:|.|:|||:|.||:||:..|.||:|||||||.||   .:....||::|.|     .
Human   124 LLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFS---PDGSRLYTHQVATSPLPRR 185

  Fly   225 WYRPPELLLGDRNYGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPDVWPGVE 289
            |||.||||.|.|.|...||:|..||||.|:...||:..|..:.:||.::.::.|:..|.|||.:.
Human   186 WYRAPELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELT 250

  Fly   290 ELELYKSIELPKNQKRRVKERLRPYVKDQTGCDLLDKLLTLDPKKRIDADTALNHDFFWTDPMPS 354
            ||..|..|.. |.|.....|.:.|.|..| ..|||.:.|...|.:||.|..||.|.:|:|.|:|:
Human   251 ELPDYNKISF-KEQVPMPLEEVLPDVSPQ-ALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPA 313

  Fly   355 DLSKM 359
            ..|::
Human   314 HPSEL 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk9	NP_477226.2	STKc_CDK9	37..347	CDD:270848	118/316 (37%)
CDK20	XP_047279074.1	STKc_CCRK	3..307	CDD:270826	118/316 (37%)