Protein Alignment Cdk9 and dyf-18

DIOPT Version :10

• Sequence 1: NP_477226.2
• Gene: Cdk9 / 37586
• FlyBaseID: FBgn0019949
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_502232.2
• Gene: dyf-18 / 186662
• WormBaseID: WBGene00010349
• Length: 323
• Species: Caenorhabditis elegans
• Alignment Length: 349
• Identity: 100/349 - (28%)
• Similarity: 162/349 - (46%)
• Gaps: 90/349 - (25%)

  Fly    49 KYEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEKEGFPITALREIRILQLLKHENVVNL 113
            :||.:...|:|.||.|..||:...:|: ||:|::::.|..:   ::..|||..|:.|.|.|::.|
 Worm     7 RYETIQVAGRGAFGLVVIARDTLTSKR-VAIKRIMVPNVSK---VSLAREISCLRNLHHRNILKL 67

  Fly   114 IEICRTKATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGEIKK-------------VMQQL 165
            :: |                   |...||..:::. .|.::||:|.|             ...|:
 Worm    68 LD-C-------------------FPSADLMSIVTE-EVPYTLGDIIKDKTRPKTEQFNRWYYTQI 111

  Fly   166 LNGLYYIHSNKILHRDMKAANVLITKHGILKLADFGLARAFSIPKNESKNRYTNRVVTLWYRPPE 230
            |:|:.|:||.:|:|||:|..|:|:|...::|:||||.| .|.:||:.:: .|...|.|.|||.||
 Worm   112 LSGIAYLHSKEIMHRDIKPENILVTSRNVVKIADFGQA-CFYMPKDPNQ-EYDVNVATRWYRAPE 174

  Fly   231 LLLGDRNYGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPDVWPGVEELELYK 295
            ||.|.:.|.|.||:|..|||:||:....||..|.:|.:|::.|..:.|:...|.||...
 Worm   175 LLFGSKKYKPDVDIWAIGCILAELVRGKPIFPGRSELEQISIIFGVLGTPNEDNWPNWR------ 233

  Fly   296 SIELPKNQKRRVKERLRPYVKDQTGCDLLDKLLTLDPKKRIDADTALNHDFFWTD-----PMPSD 355
              .:|...|                       |..:||:      ..|:   ||:     .:.::
 Worm   234 --TMPDANK-----------------------LLFEPKE------PRNN---WTEILLCKEISNN 264

  Fly   356 LSKMLSQHLQ-----SMFEYLAQP 374
            .::.|..|||     ...|.|.:|
 Worm   265 FTEFLGSHLQFFKRLKASELLKEP 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk9	NP_477226.2	STKc_CDK9	37..347	CDD:270848	91/310 (29%)
dyf-18	NP_502232.2	Protein Kinases, catalytic domain	7..289	CDD:473864	100/349 (29%)