Protein Alignment Cdk9 and cdk-5

DIOPT Version :10

• Sequence 1: NP_477226.2
• Gene: Cdk9 / 37586
• FlyBaseID: FBgn0019949
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_499783.1
• Gene: cdk-5 / 176774
• WormBaseID: WBGene00000407
• Length: 292
• Species: Caenorhabditis elegans
• Alignment Length: 301
• Identity: 126/301 - (41%)
• Similarity: 175/301 - (58%)
• Gaps: 21/301 - (6%)

  Fly    50 YEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEKEGFPITALREIRILQLLKHENVVNLI 114
            |:|:.|||:||:|.|||||.|... :.||:|:|.:|::.||.|.:|||||.||:.|||.|||.|.
 Worm     4 YDKMEKIGEGTYGTVFKARNKNSG-EIVALKRVRLDDDDEGVPSSALREICILRELKHRNVVRLY 67

  Fly   115 EICRTKATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGEIKKVMQQLLNGLYYIHSNKILH 179
            ::..::...|        |||::|:.||.....::|........:.:|.|||.||.:.|::.:||
 Worm    68 DVVHSENKLT--------LVFEYCDQDLKKFFDSLNGYMDAQTARSLMLQLLRGLSFCHAHHVLH 124

  Fly   180 RDMKAANVLITKHGILKLADFGLARAFSIPKNESKNRYTNRVVTLWYRPPELLLGDRNYGPPVDM 244
            ||:|..|:||..:|.||||||||||||.:|    ...::..|||||||||::|.|.:.|...:||
 Worm   125 RDLKPQNLLINTNGTLKLADFGLARAFGVP----VRCFSAEVVTLWYRPPDVLFGAKLYNTSIDM 185

  Fly   245 WGAGCIMAEMWTRS-PIMQGNTEQQQLTFISQLCGSFTPDVWPGVEELELYKSIEL--PKNQKRR 306
            |.||||.||:.... |:..|.....||..|.:..||.:.|.||.:.:|..||...:  |.....:
 Worm   186 WSAGCIFAEISNAGRPLFPGADVDDQLKRIFKQLGSPSEDNWPSITQLPDYKPYPIYHPTLTWSQ 250

  Fly   307 VKERLRPYVKDQTGCDLLDKLLTLDPKKRIDADTALNHDFF 347
            :...|     :..|.|||.|||..:|..|||||.||.|.:|
 Worm   251 IVPNL-----NSRGRDLLQKLLVCNPAGRIDADAALRHAYF 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk9	NP_477226.2	STKc_CDK9	37..347	CDD:270848	125/299 (42%)
cdk-5	NP_499783.1	STKc_CDK5	3..286	CDD:143344	125/299 (42%)