Protein Alignment Cdk9 and Cdk7

DIOPT Version :10

• Sequence 1: NP_477226.2
• Gene: Cdk9 / 37586
• FlyBaseID: FBgn0019949
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_034004.2
• Gene: Cdk7 / 12572
• MGIID: 102956
• Length: 346
• Species: Mus musculus
• Alignment Length: 319
• Identity: 122/319 - (38%)
• Similarity: 180/319 - (56%)
• Gaps: 36/319 - (11%)

  Fly    47 SNKYEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNE---KEGFPITALREIRILQLLKHE 108
            :.:|||:..:|:|.|..|:|||:|..| :.||:||:.:.:.   |:|...||||||::||.|.|.
Mouse     9 AKRYEKLDFLGEGQFATVYKARDKNTN-QIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHP 72

  Fly   109 NVVNLIEICRTKATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGEIKKVMQQLLNGLYYIH 173
            |::.|::        ..|::|...|||||.|.||..::.:.::..:...||..|...|.||.|:|
Mouse    73 NIIGLLD--------AFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLH 129

  Fly   174 SNKILHRDMKAANVLITKHGILKLADFGLARAFSIPKNESKNR-YTNRVVTLWYRPPELLLGDRN 237
            .:.|||||:|..|:|:.::|:|||||||||::|..|     || ||::|||.|||.||||.|.|.
Mouse   130 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSP-----NRAYTHQVVTRWYRAPELLFGARM 189

  Fly   238 YGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPDVWPGVEELELYKSIE---- 298
            ||..||||..|||:||:..|.|.:.|:::..|||.|.:..|:.|.:.||.:..|..|.:.:
Mouse   190 YGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPG 254

  Fly   299 LPKNQKRRVKERLRPYVKDQTGCDLLD---KLLTLDPKKRIDADTALNHDFFWTDPMPS 354
            :|..           ::....|.|||:   .|...:|..|..|..||...:|...|.|:
Mouse   255 VPLQ-----------HIFIAAGDDLLELIQGLFLFNPCTRTTASQALKTKYFSNRPGPT 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk9	NP_477226.2	STKc_CDK9	37..347	CDD:270848	119/310 (38%)
Cdk7	NP_034004.2	STKc_CDK7	11..308	CDD:270833	122/317 (38%)