Protein Alignment Cdk9 and Cdk1

DIOPT Version :10

• Sequence 1: NP_477226.2
• Gene: Cdk9 / 37586
• FlyBaseID: FBgn0019949
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_031685.2
• Gene: Cdk1 / 12534
• MGIID: 88351
• Length: 297
• Species: Mus musculus
• Alignment Length: 316
• Identity: 132/316 - (41%)
• Similarity: 187/316 - (59%)
• Gaps: 28/316 - (8%)

  Fly    50 YEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEKEGFPITALREIRILQLLKHENVVNLI 114
            |.|:.|||:||:|.|:|.|.:. ..:.|||||:.:::|:||.|.||:|||.:|:.|:|.|:|:|.
Mouse     4 YIKIEKIGEGTYGVVYKGRHRV-TGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQ 67

  Fly   115 EICRTKATATNGYRSTFYLVFDFCEHDLAGLLSNMN----VKFSLGEIKKVMQQLLNGLYYIHSN 175
            ::....        |..||:|:|...||...|.::.    :..||  :|..:.|:|.|:.:.||.
Mouse    68 DVLMQD--------SRLYLIFEFLSMDLKKYLDSIPPGQFMDSSL--VKSYLHQILQGIVFCHSR 122

  Fly   176 KILHRDMKAANVLITKHGILKLADFGLARAFSIPKNESKNRYTNRVVTLWYRPPELLLGDRNYGP 240
            ::||||:|..|:||...|.:|||||||||||.||...    ||:.|||||||.||:|||...|..
Mouse   123 RVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRV----YTHEVVTLWYRSPEVLLGSARYST 183

  Fly   241 PVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPDVWPGVEELELYKSIELPKNQKR 305
            |||:|..|.|.||:.|:.|:..|::|..||..|.:..|:...:|||.||.|:.||: ..||.:
Mouse   184 PVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN-TFPKWK-- 245

  Fly   306 RVKERLRPYVK--DQTGCDLLDKLLTLDPKKRIDADTALNHDFFWTDPMPSDLSKM 359
              ...|..:||  |:.|.|||.|:|..||.|||....||.|.:|  |.:.:.:.||
Mouse   246 --PGSLASHVKNLDENGLDLLSKMLVYDPAKRISGKMALKHPYF--DDLDNQIKKM 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk9	NP_477226.2	STKc_CDK9	37..347	CDD:270848	128/302 (42%)
Cdk1	NP_031685.2	STKc_CDK1_euk	3..287	CDD:270845	128/302 (42%)