Protein Alignment Cdk9 and cdk18

DIOPT Version :10

• Sequence 1: NP_477226.2
• Gene: Cdk9 / 37586
• FlyBaseID: FBgn0019949
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: XP_001919335.2
• Gene: cdk18 / 100150007
• ZFINID: ZDB-GENE-141215-51
• Length: 465
• Species: Danio rerio
• Alignment Length: 325
• Identity: 135/325 - (41%)
• Similarity: 191/325 - (58%)
• Gaps: 19/325 - (5%)

  Fly    25 RTMSLMEKQKYIEDYDFPYCDESNKYEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEKE 89
            :.:|.|.::..:.|..|   .:...|.|:.|:|:||:..|||.|.|. .:..||:|::.:::| |
Zfish   113 KPLSRMSRRASLSDIGF---GKLETYVKLGKLGEGTYATVFKGRSKL-TENLVALKEIRLEHE-E 172

  Fly    90 GFPITALREIRILQLLKHENVVNLIEICRTKATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFS 154
            |.|.||:||:.:|:.|||.|:|.|.:|..|....|        |||::.:.||...|.|.....|
Zfish   173 GAPCTAIREVSLLKNLKHANIVTLHDIIHTDRCLT--------LVFEYLDSDLKQYLDNCGNLMS 229

  Fly   155 LGEIKKVMQQLLNGLYYIHSNKILHRDMKAANVLITKHGILKLADFGLARAFSIPKNESKNRYTN 219
            :..:|..|.|||.||.|.|..||||||:|..|:||...|.|||||||||||.|:|    ...|:|
Zfish   230 MHNVKIFMFQLLRGLSYCHKRKILHRDLKPQNLLINDKGELKLADFGLARAKSVP----TKTYSN 290

  Fly   220 RVVTLWYRPPELLLGDRNYGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPDV 284
            .|||||||||::|||...|..|:||||.|||:.||.|..|:..|:|.:::|..|.:|.|:.|.:.
Zfish   291 EVVTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMATGRPMFPGSTVKEELHLIFRLMGTPTEES 355

  Fly   285 WPGVEELELYKSIELPKNQKRRVKERLRPYVKDQTGCDLLDKLLTLDPKKRIDADTALNHDFFWT 349
            |||:...|.:||...|:.:.:.:...: |.: |..|.|||..||..|.|:||.|:.:|.|.:|.|
Zfish   356 WPGITANEEFKSYLFPQYRAQALINHV-PRL-DTEGIDLLTALLLYDTKRRISAELSLRHSYFQT 418

  Fly   350  349
            Zfish   419  418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk9	NP_477226.2	STKc_CDK9	37..347	CDD:270848	131/309 (42%)
cdk18	XP_001919335.2	STKc_PCTAIRE3	129..416	CDD:270853	130/305 (43%)