Protein Alignment Cdk9 and cdk12

DIOPT Version :10

• Sequence 1: NP_477226.2
• Gene: Cdk9 / 37586
• FlyBaseID: FBgn0019949
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: XP_012826946.1
• Gene: cdk12 / 100038049
• XenbaseID: XB-GENE-493308
• Length: 1466
• Species: Xenopus tropicalis
• Alignment Length: 334
• Identity: 154/334 - (46%)
• Similarity: 214/334 - (64%)
• Gaps: 15/334 - (4%)

  Fly    48 NKYEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEKEGFPITALREIRILQLLKHENVVN 112
            :|::.:..||:||:|:|:||:: |...:.||:|||.:|||||||||||:|||:||:.|.|::|||
 Frog   708 DKFDIIGIIGEGTYGQVYKAKD-KDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHKSVVN 771

  Fly   113 LIEICRTKATATN--GYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGEIKKVMQQLLNGLYYIHSN 175
            :.||...|..|.:  ..:..|||||::.:|||.|||.:..|:||...||..|:||:.||.|.|..
 Frog   772 MKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVQFSEDHIKSFMKQLMEGLEYCHKK 836

  Fly   176 KILHRDMKAANVLITKHGILKLADFGLARAFSIPKNESKNRYTNRVVTLWYRPPELLLGDRNYGP 240
            ..||||:|.:|:|:...|.:|||||||||.:|   :|....|||:|:||||||||||||:..|.|
 Frog   837 NFLHRDIKCSNILLNNSGQIKLADFGLARLYS---SEESRPYTNKVITLWYRPPELLLGEERYTP 898

  Fly   241 PVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPDVWPGVEELELYKSIELPKNQKR 305
            .:|:|..|||:.|::|:.||.|.|.|..||..||:||||..|.|||.|.:|..:.:::..|..:|
 Frog   899 AIDVWSCGCILGELFTKKPIFQANQELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRR 963

  Fly   306 RVKERLRPYVKDQTGCDLLDKLLTLDPKKRIDADTALNHDFFWTDPMPSDLSKMLS---QHLQSM 367
            |::|.. .:| .....||||.:|||||.||..|:..|..||.    ...|:.||.:   .|.|..
 Frog   964 RLREEF-SFV-PTPALDLLDHMLTLDPSKRCTAEQTLQSDFL----KDVDVCKMATPDLPHWQDC 1022

  Fly   368 FEYLAQPRR 376
            .|..::.||
 Frog  1023 HELWSKKRR 1031

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk9	NP_477226.2	STKc_CDK9	37..347	CDD:270848	145/300 (48%)
cdk12	XP_012826946.1	STKc_CDK12	702..1003	CDD:270847	145/300 (48%)