DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment qkr58E-2 and Khdrbs2

DIOPT Version :9

Sequence 1:	NP_001286724.1	Gene:	qkr58E-2 / 37562	FlyBaseID:	FBgn0022985	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_573498.1	Gene:	Khdrbs2 / 170771	MGIID:	2159649	Length:	349	Species:	Mus musculus

Alignment Length:	312	Identity:	110/312 - (35%)
Similarity:	161/312 - (51%)	Gaps:	65/312 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 QKYMQELMTERSRMENHFPLAVKLIDEALERVQ-LNGRIPTRD-QYADVYQQRTIKLSQKVHVPI 136
            :||:.|||.|:..::..|..|.:|:.|.:|:.| .:|:....: :|.||...:.||||::|.:|:
Mouse     4 EKYLPELMAEKDSLDPSFVHASRLLAEEIEKFQGSDGKKEDEEKKYLDVISNKNIKLSERVLIPV 68

  Fly   137 KD-KKFNYVGKLLGPKGNSLRRLQEETQCKIVILGRFSMKDRAREEELRNSADAKYAHLNLPLHV 200
            |. .|||:|||||||:||||:||||||..|:.|||:.||:|:.:|||||.|.:||||||:..|||
Mouse    69 KQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKTKEEELRKSGEAKYAHLSDELHV 133

  Fly   201 EVSTIAPPAEAYARVAYALAEIRRYLTPDKHDDIRQEQYRELMEDPEAAKKLTLRQLQQQSNAAA 265
            .:...|||.|||:|:::||.||:::|.||.:|:|||||               ||:|...:.:..
Mouse   134 LIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQ---------------LRELSYLNGSEE 183

  Fly   266 SGAGGGGGGGG--------GNGNGGAAGSGSNNGNG------------------------NQRSG 298
            ||.|.|..|.|        ..|.|||.......|.|                        ..|:.
Mouse   184 SGRGRGIRGRGIRITPTAPSRGRGGAVPPPPPPGRGVLTPRGTTVTRGALPVPPIARGVPTPRAR 248

  Fly   299 G-----NYR----------QKFQQQSHYRHNEETVYFRSHNNAYHQPKPYVP 335
            |     .||          :::.....|....:...:.:::|:|..|...||
Mouse   249 GTAAVPGYRAPPPPAHDAYEEYGYDDGYGGEYDDQTYEAYDNSYVTPTQSVP 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
qkr58E-2	NP_001286724.1	SF1_like-KH	129..244	CDD:239088	66/115 (57%)
Khdrbs2	NP_573498.1	Qua1	6..57	CDD:292891	15/50 (30%)
		SF1_like-KH	61..180	CDD:239088	69/133 (52%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	181..263		16/81 (20%)
		Sam68-YY	267..321	CDD:293176	6/34 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	321..349
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845522
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8696
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11208
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.800