DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment wrapper and DIP-delta

DIOPT Version :10

Sequence 1:NP_477404.1 Gene:wrapper / 37555 FlyBaseID:FBgn0025878 Length:500 Species:Drosophila melanogaster
Sequence 2:XP_315006.5 Gene:DIP-delta / 1275796 VectorBaseID:AGAMI1_000629 Length:458 Species:Anopheles gambiae


Alignment Length:419 Identity:112/419 - (26%)
Similarity:172/419 - (41%) Gaps:79/419 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    40 IPTTVKTYENDTVQLPCTLNTPFRY-VRW-HRD-DVALVDSRHPELPPPDRIMLWPNGS---LQV 98
            ||........| ..|||.:.....| |.| |.| .:.|...||.....|...:.:.|.:   |.|
Mosquito    50 IPNVTVAVGRD-ANLPCVVEHLGTYKVAWIHIDRQMILTIHRHVISRIPRYSVTYDNSNTWLLHV 113

  Fly    99 ANVQSSDTGDYYCEMNSDSGHVVQQHAIEVQLAPQVL-IE--PSDLT---EQRIGAIFEVVCEAQ 157
            :..|..|.|.|.|::|::. .:.|...::|.:.|.:| ||  ||.:.   .|.|    .:.|.|.
Mosquito   114 SQAQQDDRGYYMCQVNTNP-MISQVGYLQVVVPPNILDIESTPSSVAVRENQNI----NMTCRAD 173

  Fly   158 GVPQPVITWRLNGNVIQPQSNTGNRQSLIL----EI-----KSRNQAGLIECVASNGVGEPAVAN 213
            |.|.|.|.||....    ||.|..|:..::    |:     .|||:.|...|:|:|||.......
Mosquito   174 GFPTPKIIWRREDG----QSITVERKKKVMVYDGEVLHLTKVSRNEMGAYLCIATNGVPPSVSKR 234

  Fly   214 VYLHVLFSPEVSIPQPVVYTKLGSRAHLECIVEAAPAATVKWFHHGLPVALGAHSTTHESELQTN 278
            :.|.|.|||.:.:|..:|...|.:...::|..||.|.|.:.|.::.:.|            |.:.
Mosquito   235 IILDVEFSPMIWVPNQLVGAPLSTDVTIDCHTEAHPRAIIYWVYNSVMV------------LPSK 287

  Fly   279 R-SVDHYVNAVR-HM-LVVKSVRNADMGQYECRASNQISVKSGSVELTGRPMPCLFKINPGTQSS 340
            : .:|:..|:.| || |.:|.:...|.|.|.|.:.|.:....||:.:...|:|.    .|..|  
Mosquito   288 KYIIDYNENSYRAHMKLTIKGLSMGDFGNYRCISKNSLGETEGSIRVYEIPLPS----TPSKQ-- 346

  Fly   341 TSHVLVWQTESLLPIMEFKLKFRQIPSNNVTRQVRTNWTELTIP--------AQATNGLIYITTY 397
            .:||           ||.|.....:.|.|.|.:|.:. .|:..|        .::.||:.:....
Mosquito   347 ITHV-----------MEPKETIPAVVSRNETIKVASQ-PEVLFPMKNDEGYAQRSPNGIPFERKG 399

  Fly   398 TL-------HGLQPASLYEVSVLARNSFG 419
            :|       :...|...:.||..||:|||
Mosquito   400 SLAIGQSFSYTDMPPKEFGVSNDARSSFG 428

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wrapperNP_477404.1 IG_like 41..118 CDD:214653 23/82 (28%)
Ig strand B 52..56 CDD:409353 1/3 (33%)
Ig strand C 64..68 CDD:409353 3/5 (60%)
Ig strand E 94..98 CDD:409353 1/6 (17%)
Ig strand F 108..113 CDD:409353 2/4 (50%)
Ig strand G 122..125 CDD:409353 1/2 (50%)
Ig 133..219 CDD:472250 30/100 (30%)
Ig strand B 150..154 CDD:409353 0/3 (0%)
Ig strand C 163..167 CDD:409353 1/3 (33%)
Ig strand E 183..187 CDD:409353 0/3 (0%)
Ig strand F 197..202 CDD:409353 1/4 (25%)
Ig strand G 211..214 CDD:409353 0/2 (0%)
Ig_3 222..311 CDD:464046 23/91 (25%)
FN3 339..431 CDD:238020 22/96 (23%)
DIP-deltaXP_315006.5 None

Return to query results.
Submit another query.