DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment wrapper and LOC1273332

DIOPT Version :10

Sequence 1:NP_477404.1 Gene:wrapper / 37555 FlyBaseID:FBgn0025878 Length:500 Species:Drosophila melanogaster
Sequence 2:XP_061499709.1 Gene:LOC1273332 / 1273332 VectorBaseID:AGAMI1_006377 Length:610 Species:Anopheles gambiae


Alignment Length:559 Identity:146/559 - (26%)
Similarity:245/559 - (43%) Gaps:114/559 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 HMCSVVRCLLAALI----LGQVQAELDFNNDLENSQK-FKSIPTTVKTYENDTVQLPCTLNTPFR 63
            |:..|...||..::    :|:..:::     |..::. |.|.....|....||:.|||.:.:|..
Mosquito   103 HLLLVAAVLLTHMLVNIRIGEAASQI-----LNKAEPLFISRSEAFKFAVGDTITLPCEVASPGT 162

  Fly    64 YV-RWHRDDVALVDSRHPELPPPDRIMLWPNGSLQVANVQSSDTGDYYCEMNS-DSGHVVQQHAI 126
            || .|.| .:|::.:...::.|..|:.|....|||:.:....|.|||.|::.. |...:.  |::
Mosquito   163 YVLAWKR-GIAILTAGSVKVTPDPRVRLVNGYSLQIRDAVPQDAGDYICQIAMLDPREIT--HSV 224

  Fly   127 EVQLAPQVL-IEPSDLTEQRIGAIFEVVCEAQGVPQPVITWRLNGNVIQPQSNTGNRQSLILEIK 190
            |:.:.|::. :......:.|.|:...:.|.|.|.|.|.|||....|::............::|..
Mosquito   225 EILVPPKITHVTSGGHLQVRKGSPVRLECSATGNPMPNITWTRKNNLLPNGEEQFTNPVYVIENM 289

  Fly   191 SRNQAGLIECVASNGVGEPAVANVYLHVLFSPEVSIPQPVVYTKLGSRAHLECIV--EAAPAATV 253
            .|::.|...|.|:||||:.|.:.:.||||:.||:|:..|.||:..|..|.|.|||  |:.| ..|
Mosquito   290 DRHKGGTYICTANNGVGQVATSQIILHVLYPPEISVENPTVYSGEGQEAMLVCIVHGESQP-EKV 353

  Fly   254 KWFHHGLPVALGAHSTTHESELQTNRSVDHYV--NAVRHMLVVKSVRNADMGQYECRASNQISVK 316
            .|               |:..:|.:::..|.:  ...||.|:::.|...|.|.|.|.|.||:...
Mosquito   354 LW---------------HKDTMQIDQTERHVIENRGARHTLIIRKVHPQDFGNYSCIADNQLGKT 403

  Fly   317 SGSVELTGRPMPCLFKINPGTQSSTSHVLVWQTESLLPIMEFKLKFRQIPSNNV----------- 370
            ..:|.|||:|...:|:..|.:|....:.:.|..:|..||.||||.:||:..:.:           
Mosquito   404 RKTVTLTGKPKTAVFRSVPNSQWKDKYNISWIVDSHSPIEEFKLYYRQVDGDTLQAHDGIFLDNR 468

  Fly   371 --------------TRQV--------------------RTNWTELTIPA-----QATNGLIYITT 396
                          .|::                    :|:|.::.:||     ..|.|:    :
Mosquito   469 KLHHSYAGDNMLDYNRKINSYDSYSYNNGYHNLHHKWSKTDWRDIVLPAFPYSHHYTQGM----S 529

  Fly   397 YTLHGLQPASLYEVSVLARNSFGWSDNSKIVRFATGGEVELPNYSTESELQDDFTEEDFHNEITQ 461
            |.:.||:|...||..|.:||.:||||.|:...|.|.        :|::|::|        ..:|.
Mosquito   530 YLIRGLEPDQQYEARVQSRNRYGWSDFSESFLFTTS--------NTDTEIRD--------LSVTH 578

  Fly   462 RSEVLSASMMFNSGSVNGRGGISAFIYSLCLINILRLIS 500
            .|. ..||::|.|       .|...:.:|.|:.:.||:|
Mosquito   579 YSS-SRASVIFAS-------EIRCLLGALALVAVCRLVS 609

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wrapperNP_477404.1 IG_like 41..118 CDD:214653 24/78 (31%)
Ig strand B 52..56 CDD:409353 1/3 (33%)
Ig strand C 64..68 CDD:409353 2/4 (50%)
Ig strand E 94..98 CDD:409353 2/3 (67%)
Ig strand F 108..113 CDD:409353 3/4 (75%)
Ig strand G 122..125 CDD:409353 0/2 (0%)
Ig 133..219 CDD:472250 23/86 (27%)
Ig strand B 150..154 CDD:409353 0/3 (0%)
Ig strand C 163..167 CDD:409353 2/3 (67%)
Ig strand E 183..187 CDD:409353 0/3 (0%)
Ig strand F 197..202 CDD:409353 1/4 (25%)
Ig strand G 211..214 CDD:409353 0/2 (0%)
Ig_3 222..311 CDD:464046 28/92 (30%)
FN3 339..431 CDD:238020 32/141 (23%)
LOC1273332XP_061499709.1 None

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