Protein Alignment Rtf1 and rtfo-1

DIOPT Version :10

• Sequence 1: NP_611665.1
• Gene: Rtf1 / 37554
• FlyBaseID: FBgn0034722
• Length: 775
• Species: Drosophila melanogaster
• Sequence 2: NP_505473.1
• Gene: rtfo-1 / 179345
• WormBaseID: WBGene00009103
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 798
• Identity: 220/798 - (27%)
• Similarity: 357/798 - (44%)
• Gaps: 241/798 - (30%)

  Fly    12 SNSSDSDSESETNLESDLMSLAKKRKKPQTAAKSSSRSDSDSDWANNKAGAPSSKKKKRQKPSRD 76
            |:|..:.|:.||           ||:.|.|     |.|||||| |..|.|.|.         |.|
 Worm     2 SSSESASSDEET-----------KRRAPAT-----SDSDSDSD-AGPKPGKPL---------STD 40

  Fly    77 SSSSESNWDDDSQDERQPARQSPAQTQQEHKPPEQASQPAQLSEQEEGEVSDSDSDKSKSNSSSS 141
            ||:|:|   |..:.:.:||::. ..|:::.:
 Worm    41 SSASDS---DAEKPQAKPAKKK-TLTKRKRR---------------------------------- 67

  Fly   142 GSDSSSSSSSSDSEFDDGFDDDLMGDDEDRRRLNGLSEKERETEIYKRIEQREIMRTRWEIERKL 206
                  ::.|||   ||..||||..|.||:.|...|:|.|:|.||::|:|.||....|.||.:
 Worm    68 ------ATGSSD---DDQVDDDLFADKEDKARWKKLTELEKEQEIFERMEARENAIAREEIAQ-- 121

  Fly   207 KLARRGEKNQEKSKNKGERAKKKKEKREKKARKAREAQAPLPTQASTSTLLDVEPKPSNEVRSAS 271
            :||::.:|:.||.        .|.|||.|......:|.:|
 Worm   122 QLAKKAKKSSEKG--------VKTEKRRKMNSGGSDAGSP------------------------- 153

  Fly   272 PLSTPALNRDAASTSAAVASIMPDDAASSAGVSDYFDHKERSKERKKNVEANKTDDKRSNAMALL 336
                   .|.|:|.|         |:...|..     |:.....||         .|..|||..|
 Worm   154 -------KRKASSDS---------DSEMDAAF-----HRPSDINRK---------HKEKNAMDAL 188

  Fly   337 KAKREGKAKREEEEAKRMAEKDRDDDKEELDSVSGCKSAVKLKASEIYSDDSGSSDWDEEEKPAG 401
            |.||           |.:.:|:..::...:|:|.|.              :||||.
 Worm   189 KNKR-----------KEIEKKNAKNEALSIDAVFGA--------------NSGSSS--------- 219

  Fly   402 KRSRSNSSKASSESEDEEKAPQRPVFITTRE-----------DLNKLRLSRYKMERFVNLPIFES 455
              |.|:|..:.|.|...|.:|:|   ::.::           :|.:.||||:|:...::.|.|:|
 Worm   220 --SSSSSESSRSSSSSRESSPER---VSEKDKIVKKDVDGLSELRRARLSRHKLSLMIHAPFFDS 279

  Fly   456 TVLNCFVRISIGN-NGQKPVYRVAEIVGVVETGKIYSLGTTRTNRGLRLKHGTQERVFRLEFISN 519
            ||:.|:||:..|. :|....||:.:||||.|:.|:|.|...:||:.::.::|..||.||::|:||
 Worm   280 TVVGCYVRLGQGQMSGSGSKYRIWKIVGVEESNKVYELEGKKTNKIIKCQNGGSERPFRMQFVSN 344

  Fly   520 QEFTENEFNKWNEVCQQSHVQMPTIDLIAIKQNDIKKALNYEFKDEDVDKIVEEKNRFRNRPTNY 584
            .:|.:.||::|...|:: |..:||:|::..|:.||:||:|:::.|::||.:::||::::..|.|:
 Worm   345 ADFEQIEFDEWLLACKR-HGNLPTVDIMDKKKQDIEKAINHKYSDKEVDLMIKEKSKYQTVPRNF 408

  Fly   585 AMKKTCLMKERDAAMLRGDYDIAQDLGQQIDELENRASELDKRRSHTLNLISYINDRNRKKNVED 649
            ||.|....|:::.|..|||...|:.:..:|||:|.:|.||:|.||.:::.|::||.|||.|
 Worm   409 AMTKANWSKQKELAQQRGDIREAEQIQTKIDEIERQADELEKERSKSISAIAFINHRNRSK---- 469

  Fly   650 AEKAILEEARANKGLKI-----SDPFTRRITQPRMGFKGAK--------------------KDED 689
                 :::...:..|||     .|||||:....|: ..|:|                    ||:.
 Worm   470 -----IKDQVLSGQLKIEENSQDDPFTRKKGGMRV-VSGSKSRLDGTLSASSSTTNLSDGGKDKS 528

  Fly   690 DMQLAPLPPPPPGKKRPNEAGTSSASVRSTDSKDYSLYSLHDFDIDLDVPLPVNTNSVPKPASKP 754
            .....|..|||           |:...:.||     :.||||||:|:|:....:.::.....:|.
 Worm   529 SSLAKPTQPPP-----------STQIKKKTD-----ISSLHDFDLDIDLGKLKDFSTPESSGNKR 577

  Fly   755 AETVSKRSLNLEDYKKKR 772
            ....|.:.::|.||:.:|
 Worm   578 PSISSSKGVSLSDYRMRR 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rtf1	NP_611665.1	COG5296	<433..677	CDD:227615	92/249 (37%)
		Plus-3	434..534	CDD:460817	40/100 (40%)
rtfo-1	NP_505473.1	COG5296	82..503	CDD:227615	156/535 (29%)
		Plus3	252..360	CDD:197843	40/107 (37%)