Protein Alignment Rtf1 and rtfo-1

DIOPT Version :9

• Sequence 1: NP_001286717.1
• Gene: Rtf1 / 37554
• FlyBaseID: FBgn0034722
• Length: 775
• Species: Drosophila melanogaster
• Sequence 2: NP_505473.1
• Gene: rtfo-1 / 179345
• WormBaseID: WBGene00009103
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 798
• Identity: 220/798 - (27%)
• Similarity: 357/798 - (44%)
• Gaps: 241/798 - (30%)

  Fly    12 SNSSDSDSESETNLESDLMSLAKKRKKPQTAAKSSSRSDSDSDWANNKAGAPSSKKKKRQKPSRD 76
            |:|..:.|:.||           ||:.|.|     |.|||||| |..|.|.|.         |.|
 Worm     2 SSSESASSDEET-----------KRRAPAT-----SDSDSDSD-AGPKPGKPL---------STD 40

  Fly    77 SSSSESNWDDDSQDERQPARQSPAQTQQEHKPPEQASQPAQLSEQEEGEVSDSDSDKSKSNSSSS 141
            ||:|:|   |..:.:.:||::. ..|:::.:
 Worm    41 SSASDS---DAEKPQAKPAKKK-TLTKRKRR---------------------------------- 67

  Fly   142 GSDSSSSSSSSDSEFDDGFDDDLMGDDEDRRRLNGLSEKERETEIYKRIEQREIMRTRWEIERKL 206
                  ::.|||   ||..||||..|.||:.|...|:|.|:|.||::|:|.||....|.||.:
 Worm    68 ------ATGSSD---DDQVDDDLFADKEDKARWKKLTELEKEQEIFERMEARENAIAREEIAQ-- 121

  Fly   207 KLARRGEKNQEKSKNKGERAKKKKEKREKKARKAREAQAPLPTQASTSTLLDVEPKPSNEVRSAS 271
            :||::.:|:.||.        .|.|||.|......:|.:|
 Worm   122 QLAKKAKKSSEKG--------VKTEKRRKMNSGGSDAGSP------------------------- 153

  Fly   272 PLSTPALNRDAASTSAAVASIMPDDAASSAGVSDYFDHKERSKERKKNVEANKTDDKRSNAMALL 336
                   .|.|:|.|         |:...|..     |:.....||         .|..|||..|
 Worm   154 -------KRKASSDS---------DSEMDAAF-----HRPSDINRK---------HKEKNAMDAL 188

  Fly   337 KAKREGKAKREEEEAKRMAEKDRDDDKEELDSVSGCKSAVKLKASEIYSDDSGSSDWDEEEKPAG 401
            |.||           |.:.:|:..::...:|:|.|.              :||||.
 Worm   189 KNKR-----------KEIEKKNAKNEALSIDAVFGA--------------NSGSSS--------- 219

  Fly   402 KRSRSNSSKASSESEDEEKAPQRPVFITTRE-----------DLNKLRLSRYKMERFVNLPIFES 455
              |.|:|..:.|.|...|.:|:|   ::.::           :|.:.||||:|:...::.|.|:|
 Worm   220 --SSSSSESSRSSSSSRESSPER---VSEKDKIVKKDVDGLSELRRARLSRHKLSLMIHAPFFDS 279

  Fly   456 TVLNCFVRISIGN-NGQKPVYRVAEIVGVVETGKIYSLGTTRTNRGLRLKHGTQERVFRLEFISN 519
            ||:.|:||:..|. :|....||:.:||||.|:.|:|.|...:||:.::.::|..||.||::|:||
 Worm   280 TVVGCYVRLGQGQMSGSGSKYRIWKIVGVEESNKVYELEGKKTNKIIKCQNGGSERPFRMQFVSN 344

  Fly   520 QEFTENEFNKWNEVCQQSHVQMPTIDLIAIKQNDIKKALNYEFKDEDVDKIVEEKNRFRNRPTNY 584
            .:|.:.||::|...|:: |..:||:|::..|:.||:||:|:::.|::||.:::||::::..|.|:
 Worm   345 ADFEQIEFDEWLLACKR-HGNLPTVDIMDKKKQDIEKAINHKYSDKEVDLMIKEKSKYQTVPRNF 408

  Fly   585 AMKKTCLMKERDAAMLRGDYDIAQDLGQQIDELENRASELDKRRSHTLNLISYINDRNRKKNVED 649
            ||.|....|:::.|..|||...|:.:..:|||:|.:|.||:|.||.:::.|::||.|||.|
 Worm   409 AMTKANWSKQKELAQQRGDIREAEQIQTKIDEIERQADELEKERSKSISAIAFINHRNRSK---- 469

  Fly   650 AEKAILEEARANKGLKI-----SDPFTRRITQPRMGFKGAK--------------------KDED 689
                 :::...:..|||     .|||||:....|: ..|:|                    ||:.
 Worm   470 -----IKDQVLSGQLKIEENSQDDPFTRKKGGMRV-VSGSKSRLDGTLSASSSTTNLSDGGKDKS 528

  Fly   690 DMQLAPLPPPPPGKKRPNEAGTSSASVRSTDSKDYSLYSLHDFDIDLDVPLPVNTNSVPKPASKP 754
            .....|..|||           |:...:.||     :.||||||:|:|:....:.::.....:|.
 Worm   529 SSLAKPTQPPP-----------STQIKKKTD-----ISSLHDFDLDIDLGKLKDFSTPESSGNKR 577

  Fly   755 AETVSKRSLNLEDYKKKR 772
            ....|.:.::|.||:.:|
 Worm   578 PSISSSKGVSLSDYRMRR 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rtf1	NP_001286717.1	Plus3	428..535	CDD:197843	40/118 (34%)
rtfo-1	NP_505473.1	COG5296	82..503	CDD:227615	156/535 (29%)
		Plus3	252..360	CDD:197843	40/107 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167455
Domainoid	1	1.000	120	1.000	Domainoid score	I3575
eggNOG	1	0.900	-	-		E1_COG5296
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	246	1.000	Inparanoid score	I2043
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55546
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003630
OrthoInspector	1	1.000	-	-		oto17975
orthoMCL	1	0.900	-	-		OOG6_103917
Panther	1	1.100	-	-	LDO	PTHR13115
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1264
SonicParanoid	1	1.000	-	-		X3500
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.790